Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | OXTR | P30559 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | WNT3A | P56704 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5116737 | 0.86 | LDHA (0.50) | LDHABAZ2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5106786 | 0.85 | LDHA (0.49) | LDHABAZ2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6027504 | 0.81 | HTT (0.49) | ALDH1A1GLATSHROXTRNPC1 | |
| SCHEMBL28760239 | 0.79 | BAZ2B (0.45) | LDHABAZ2BALDH1A1OXTRNPC1 | |
| SCHEMBL27654625 | 0.79 | ALDH1A1 (0.60) | ALDH1A1GLATSHRNPC1RAB9A | |
| SCHEMBL5106595 | 0.76 | LDHA (0.53) | LDHABAZ2BHPGDSCYP11B1FFAR1 | |
| SCHEMBL380050 | 0.74 | ALDH1A1 (0.76) | ALDH1A1GLATSHRNPC1RAB9A | |
| SCHEMBL5102869 | 0.74 | LDHA (0.50) | LDHABAZ2BOXTRHPGDSCYP11B1 | |
| SCHEMBL13327616 | 0.73 | RAB9A (0.48) | LDHABAZ2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15421297 | 0.73 | CYP11B1 (0.50) | LDHABAZ2BALDH1A1RAB9AHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720829-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005090292-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |