Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027482 | 0.81 | LDHA (0.49) | HTTALDH1A1TSHRGLAHPGDS | |
| SCHEMBL27654625 | 0.78 | ALDH1A1 (0.60) | HTTALDH1A1TSHRGLASMN1; SMN2 | |
| SCHEMBL380050 | 0.77 | ALDH1A1 (0.76) | HTTALDH1A1TSHRGLASMN1; SMN2 | |
| SCHEMBL28725989 | 0.75 | ALDH1A1 (0.68) | HTTALDH1A1TSHRGLASMN1; SMN2 | |
| SCHEMBL6027580 | 0.75 | ALDH1A1 (0.44) | HTTALDH1A1TSHRGLASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3454478 | 0.75 | ALDH1A1 (0.73) | HTTALDH1A1TSHRGLASMN1; SMN2 | |
| SCHEMBL27811431 | 0.75 | ALDH1A1 (0.73) | HTTALDH1A1TSHRGLASMN1; SMN2 | |
| SCHEMBL6027792 | 0.73 | ALDH1A1 (0.45) | HTTALDH1A1TSHRGLASMN1; SMN2 | |
| SCHEMBL4763042 | 0.72 | HTT (0.45) | HTTALDH1A1TSHRGLATP53 | |
| SCHEMBL6671752 | 0.71 | HTT (0.65) | HTTALDH1A1TSHRGLATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720829-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005090292-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |