Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027580 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDNPC1RAB9A | |
| SCHEMBL3463002 | 0.79 | USP30 (0.53) | ALDH1A1MAPTUSP30KDM4ESMN1; SMN2 | |
| SCHEMBL5508940 | 0.78 | POLB (0.60) | ALDH1A1GLATSHRHTTSMN1; SMN2 | |
| SCHEMBL4172587 | 0.78 | HCAR3 (0.40) | ALDH1A1GLATSHRHTTSMN1; SMN2 | |
| SCHEMBL27654625 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDNPC1RAB9A | |
| SCHEMBL1117875 | 0.75 | HCAR3 (0.48) | ALDH1A1MAPTTSHRHTTPOLB | |
| SCHEMBL6027504 | 0.73 | HTT (0.49) | ALDH1A1MAPTHPGDNPC1RAB9A | |
| SCHEMBL16404619 | 0.72 | CKS1B (0.52) | MAPTNPC1RAB9AUSP30SMN1; SMN2 | |
| SCHEMBL30500249 | 0.72 | POLB (0.38) | ALDH1A1USP30TSHRSMN1; SMN2POLB | |
| SCHEMBL28525227 | 0.72 | POLB (0.38) | ALDH1A1USP30TSHRSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720829-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005090292-A1 | DERIVATIVES OF HETEROARYL-ALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |