Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29518366 | 0.94 | TDP1 (0.38) | TSHRCYP3A4TXNRD1TDP1ALDH1A1 | |
| SCHEMBL40986 | 0.94 | TDP1 (0.38) | TSHRCYP3A4TXNRD1TDP1ALDH1A1 | |
| SCHEMBL2034272 | 0.78 | TDP1 (0.42) | TSHRCYP3A4TXNRD1TDP1ALDH1A1 | |
| SCHEMBL1582439 | 0.78 | TDP1 (0.42) | TSHRCYP3A4TXNRD1TDP1ALDH1A1 | |
| SCHEMBL3040192 | 0.78 | CTSB (0.51) | TSHRCYP3A4TDP1ALDH1A1MAPT | |
| SCHEMBL1128565 | 0.78 | TSHR (0.44) | TSHRCYP3A4TXNRD1TDP1ALDH1A1 | |
| SCHEMBL30660529 | 0.78 | TXNRD1 (0.56) | TXNRD1MAPTHTTS1PR4S1PR1 | |
| SCHEMBL3062790 | 0.78 | TXNRD1 (0.56) | TXNRD1MAPTHTTS1PR4S1PR1 | |
| Bromide SCHEMBL6299103 | 0.77 | TDP1 (0.41) | TSHRCYP3A4TXNRD1TDP1ALDH1A1 | |
| SCHEMBL29154637 | 0.76 | GPR35 (0.43) | TSHRCYP3A4TDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060194782-A1 | Pharmacologically active imidazo[4,5-c] pyridines | ALTANA PHARMA AG (DE) | 2006-08-31 | — | — | US | disclosed |
| EP-1670795-A1 | PHARMACOLOGICALLY ACTIVE IMIDAZO 4,5-C PYRIDINES | ALTANA Pharma AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005026164-A1 | PHARMACOLOGICALLY ACTIVE IMIDAZO[4,5-C]PYRIDINES | ALTANA PHARMA AG (DE) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194782-A1 | Pharmacologically active imidazo[4,5-c] pyridines | GIPR, VIP, PGC | TSHR 1113/4885CYP3A4 29/4885TXNRD1 1289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.