SCHEMBL6028468

SCHEMBL6028468

CCOC(C)N(O)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TP53 P04637 2/20 0.40
LMNA P02545 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.38
GLA P06280 1/20 0.37
TSHR P16473 1/20 0.37
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
MAPT P10636 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
POLB P06746 1/20 0.33
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2572166 0.80 L3MBTL1 (0.40) SMN1; SMN2ALDH1A1TP53LMNAL3MBTL1
SCHEMBL1637983 0.78 L3MBTL1 (0.39) SMN1; SMN2ALDH1A1TP53LMNAL3MBTL1
SCHEMBL10472027 0.77 TP53 (0.38) SMN1; SMN2ALDH1A1TP53LMNAL3MBTL1
Oxalic Acid SCHEMBL29203689 0.77 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1TP53LMNAL3MBTL1
SCHEMBL27690534 0.74 ALDH1A1 (0.49) SMN1; SMN2ALDH1A1TP53LMNAL3MBTL1
SCHEMBL6399613 0.72 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1TP53LMNAGLA
SCHEMBL29199658 0.72 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1TP53LMNAL3MBTL1
SCHEMBL11671231 0.71 KMT2A (0.44) SMN1; SMN2ALDH1A1TP53LMNAL3MBTL1
SCHEMBL28590655 0.70 L3MBTL1 (0.33) SMN1; SMN2ALDH1A1TP53LMNAL3MBTL1
SCHEMBL9354511 0.70 ALOX5 (0.41) SMN1; SMN2ALDH1A1TP53LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1635220-A2 Oxime derivatives and the use thereof as photoinitiators Ciba Specialty Chemicals Holding Inc. (CH) 2006-03-15 EP disclosed