SCHEMBL6029243

SCHEMBL6029243

Nc1ccc(Oc2ccc(N)cc2C=CCO)c(C=CCO)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
CYP3A4 P08684 1/20 0.34
RECQL P46063 1/20 0.34
CYP19A1 P11511 5/20 0.34
HTR2A P28223 1/20 0.34
SLC6A4 P31645 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.33
GAA P10253 4/20 0.32
MAPT P10636 3/20 0.32
KDM4E B2RXH2 2/20 0.32
HTT P42858 2/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
NQO2 P16083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6028425 0.84 HTR2A (0.38) ALDH1A1CYP19A1HTR2ASLC6A4GAA
SCHEMBL6030217 0.82 HTR2A (0.37) ALDH1A1CYP19A1HTR2ASLC6A4GAA
SCHEMBL6310979 0.79 RECQL (0.37) ALDH1A1CYP3A4RECQLCYP19A1MAPT
SCHEMBL6310983 0.79 RECQL (0.37) ALDH1A1CYP3A4RECQLCYP19A1MAPT
SCHEMBL6029528 0.76 ALDH1A1 (0.35) ALDH1A1CYP3A4RECQLCYP19A1HTR2A
SCHEMBL11794717 0.76 HMGCR (0.44) ALDH1A1CYP3A4CYP19A1HTR2ASLC6A4
SCHEMBL6028430 0.69 CYP19A1 (0.36) ALDH1A1CYP19A1HTR2ASLC6A4GAA
SCHEMBL6834438 0.69 ALDH1A1 (0.36) ALDH1A1CYP19A1HTR2ASLC6A4PTGDR2
SCHEMBL7450872 0.69 CYP19A1 (0.49) ALDH1A1CYP19A1HTR2ASLC6A4GAA
SCHEMBL7450858 0.69 CYP19A1 (0.49) ALDH1A1CYP19A1HTR2ASLC6A4GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220283032-A1 Hair Colorant Assessment, Selection And Formulation System Innovative Beauty LLC (US) 2022-09-08 US disclosed
US-11378457-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2022-07-05 US disclosed
US-11137291-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2021-10-05 US disclosed
US-6986886-B2 Hair conditioning compositions and their use in hair coloring compositions THE PROCTER & GAMBLE COMPANY (US) 2006-01-17 US disclosed
US-20040158941-A1 Hair colouring and conditioning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-08-19 US disclosed
US-20040158938-A1 Method for colouring hair THE PROCTER & GAMBLE COMPANY 2004-08-19 US disclosed
US-6758866-B2 AQUEOUS SOLUTION OF CHELATE COMPOUND, OXIDATION COLOR DYE AND COUPLER UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-07-06 US disclosed
US-6695888-B2 COMPLEX TRANSITION METAL HAIR DYE UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. 2004-02-24 US disclosed
US-20040019980-A1 One step hair coloring compositions using salts UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2004-02-05 US disclosed
US-20030219399-A1 Hair conditioning compositions and their use in hair colouring compositions THE PROCTER & GAMBLE COMPANY (US) 2003-11-27 US disclosed
EP-0951270-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-10-27 EP disclosed
WO-1999026508-A1 PRODUCT APPLICATOR THE PROCTER & GAMBLE COMPANY (US) 1999-06-03 WO disclosed
EP-0918503-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-06-02 EP disclosed
EP-0869769-A1 HAIR BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-10-14 EP disclosed
WO-1998027943-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027944-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027942-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1998027945-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-07-02 WO disclosed
WO-1997024108-A1 HAIR BLEACHING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed
WO-1997024105-A1 HAIR COLORING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030219399-A1 Hair conditioning compositions and their use in hair colouring compositions CD99, HLA-C, PLOD1 ALDH1A1 1318/4885CYP3A4 4370/4885RECQL 4435/4885
US-20040158941-A1 Hair colouring and conditioning compositions FNIP1, CUTA, SHH ALDH1A1 1162/4885CYP3A4 4246/4885RECQL 1159/4885
US-20040158938-A1 Method for colouring hair COX5B, SHH, DNMT3A ALDH1A1 209/4885CYP3A4 1944/4885RECQL 2698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.