Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030604 | 1.00 | KMT2A (0.53) | KMT2AMAPK1SMN1; SMN2LMNAGAA | |
| SCHEMBL526159 | 0.87 | KMT2A (0.59) | KMT2AMAPK1SMN1; SMN2LMNAGAA | |
| SCHEMBL6031138 | 0.85 | MEN1 (0.41) | KMT2AMEN1 | |
| SCHEMBL27637680 | 0.83 | KMT2A (0.52) | KMT2AMAPK1SMN1; SMN2LMNAGAA | |
| SCHEMBL6029698 | 0.83 | KMT2A (0.52) | KMT2AMAPK1SMN1; SMN2LMNAGAA | |
| SCHEMBL3456624 | 0.83 | KMT2A (0.56) | KMT2AMAPK1SMN1; SMN2LMNAGAA | |
| SCHEMBL68154 | 0.83 | SLC6A9 (0.38) | KMT2AMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL6489914 | 0.83 | SLC6A9 (0.38) | KMT2AMAPK1MEN1 | |
| SCHEMBL6553866 | 0.81 | LMNA (0.60) | KMT2AMAPK1SMN1; SMN2LMNAGAA | |
| SCHEMBL27618514 | 0.78 | KMT2A (0.51) | KMT2AMAPK1SMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074742-B2 | Pyridinyl amides and imides for use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-07-11 | — | — | US | disclosed |
| US-20050009889-A1 | Synergistic fungicide compositions containing at least one n-(2-pyridinyl) 1-3-pyridinecarboxamide derivative and one or more further fungicides useful for controlling fungal plant diseases | E.I. DU PONE DE NEMOURS AND COMPANY | 2005-01-13 | — | — | US | disclosed |
| US-20040044040-A1 | Pyridinyl amides and imides for use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009889-A1 | Synergistic fungicide compositions containing at least one n-(2-pyridinyl) 1-3-pyridinecarboxamide derivative and one or more further fungicides useful for controlling fungal plant diseases | CYC1, ME3, CYP11B1 | KMT2A 2462/4885MAPK1 1882/4885SMN1; SMN2 3210/4885 |
| US-20040044040-A1 | Pyridinyl amides and imides for use as fungicides | CBR1, CBR3, AOC3 | KMT2A 2759/4885MAPK1 1077/4885SMN1; SMN2 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.