Sugi Predict

Sugi Predict / Compounds / SCHEMBL526159

SCHEMBL526159

SCHEMBL526159

CC(NC(=O)c1c(Cl)cccc1Cl)c1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 7/20 0.59
▸ MEN1 O00255 6/20 0.59
▸ SMN1; SMN2 Q16637 3/20 0.59
▸ MAPT P10636 1/20 0.59
▸ NPSR1 Q6W5P4 1/20 0.59
▸ MAPK1 P28482 1/20 0.54
▸ LMNA P02545 3/20 0.53
▸ GAA P10253 3/20 0.51
▸ POLB P06746 2/20 0.48
▸ KDM4E B2RXH2 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ HTT P42858 1/20 0.45
▸ PKM P14618 2/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3456624 0.88 KMT2A (0.56) KMT2AMEN1SMN1; SMN2MAPTNPSR1
SCHEMBL6030503 0.87 KMT2A (0.53) KMT2AMEN1SMN1; SMN2MAPTNPSR1
SCHEMBL6030604 0.87 KMT2A (0.53) KMT2AMEN1SMN1; SMN2MAPTNPSR1
SCHEMBL6553866 0.86 LMNA (0.60) KMT2AMEN1SMN1; SMN2MAPTNPSR1
SCHEMBL16240114 0.85 KMT2A (0.53) KMT2AMEN1SMN1; SMN2MAPTNPSR1
SCHEMBL3457836 0.84 PTGER4 (0.43) KMT2AMEN1GAAALDH1A1
SCHEMBL6029698 0.82 KMT2A (0.52) KMT2AMEN1SMN1; SMN2MAPK1LMNA
SCHEMBL876740 0.82 KMT2A (0.39) KMT2AMEN1SMN1; SMN2MAPTNPSR1
SCHEMBL27637680 0.82 KMT2A (0.52) KMT2AMEN1SMN1; SMN2MAPK1LMNA
SCHEMBL5202247 0.80 KMT2A (0.53) KMT2AMEN1SMN1; SMN2MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2645856-A1 USE OF FLUOPYRAM FOR CONTROLLING NEMATODES IN CROPS AND FOR INCREASING YIELD Bayer Intellectual Property GmbH (DE) 2013-10-09 — — EP claimed
US-20130232645-A1 USE OF ACTIVE INGREDIENTS FOR CONTROLLING NEMATODES IN NEMATODE-RESISTANT CROPS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-09-05 — — US claimed
EP-1484970-B1 BENZAMIDES AND COMPOSITIONS COMPRISING BENZAMIDES FOR USE AS FUNGICIDES DU PONT (US) 2013-06-26 — — EP claimed
WO-2012072660-A1 USE OF FLUOPYRAM FOR CONTROLLING NEMATODES IN CROPS AND FOR INCREASING YIELD BAYER CROPSCIENCE AG (DE) 2012-06-07 — — WO claimed
EP-2460406-A1 Use of fluopyram for controlling nematodes in nematode resistant crops Bayer CropScience AG (DE) 2012-06-06 — — EP claimed
EP-1389614-A1 Novel N-[2-(2-Pyridyl)ethyl]benzamide derivatives as fungicides Bayer CropScience S.A. (FR) 2004-02-18 — — EP claimed
CN-109952028-B Fluopyram-containing formulations for controlling nematodes 拜耳作物科学股份公司 2022-05-27 — — CN disclosed
CN-109952028-B Fluopyram-containing formulations for controlling nematodes 拜耳作物科学股份公司 2022-05-27 — — CN disclosed
US-11241010-B2 Use of succinate dehydrogenase inhibitors for extending shelf life of fruits and vegetables BAYER INTELLECTUAL PROPERTY GMBH (DE) 2022-02-08 — — US disclosed
EP-3509420-B1 FORMULATIONS CONTAINING FLUOPYRAM FOR THE CONTROL OF NEMATODES BAYER CROPSCIENCE AG (DE) 2022-01-05 — — EP disclosed
US-20210282391-A1 FORMULATIONS CONTAINING FLUOPYRAM FOR THE CONTROL OF NEMATODES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-09-16 — — US disclosed
US-20210282391-A1 FORMULATIONS CONTAINING FLUOPYRAM FOR THE CONTROL OF NEMATODES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-09-16 — — US disclosed
US-10829648-B2 Succinate dehydrogenase inhibitor containing compositions ARCH WOOD PROTECTION, INC. (US) 2020-11-10 — — US disclosed
US-20100222397-A1 Use of Succinate Dehydrogenase Inhibitors For Controlling Powdery Mildew Primary Infections BAYER CROPSCIENCE AG (DE) 2010-09-02 — — US disclosed
WO-2010091803-A2 USE OF SUCCINATE DEHYDROGENASE INHIBITORS FOR EXTENDING SHELF LIFE OF FRUITS AND VEGETABLES BAYER CROPSCIENCE AG (DE) 2010-08-19 — — WO disclosed
EP-2100506-A2 Uses of fluopyram Bayer CropScience AG (DE) 2009-09-16 — — EP disclosed
EP-2100506-A2 Uses of fluopyram Bayer CropScience AG (DE) 2009-09-16 — — EP disclosed
US-20050164999-A1 Benzamides and compositions benzamides for use as fungicizide E. I. DU PONT DE NEMOURS AND COMPANY 2005-07-28 — — US disclosed
EP-1389614-A1 Novel N-[2-(2-Pyridyl)ethyl]benzamide derivatives as fungicides Bayer CropScience S.A. (FR) 2004-02-18 — — EP disclosed
EP-1389614-A1 Novel N-[2-(2-Pyridyl)ethyl]benzamide derivatives as fungicides Bayer CropScience S.A. (FR) 2004-02-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050164999-A1 Benzamides and compositions benzamides for use as fungicizide CYC1, ME3, ME2 KMT2A 1890/4885MEN1 2554/4885SMN1; SMN2 3225/4885
US-20210282391-A1 FORMULATIONS CONTAINING FLUOPYRAM FOR THE CONTROL OF NEMATODES FLNB, FPR2, FLNA KMT2A 1041/4885MEN1 4739/4885SMN1; SMN2 1647/4885
US-20130232645-A1 USE OF ACTIVE INGREDIENTS FOR CONTROLLING NEMATODES IN NEMATODE-RESISTANT CROPS MLN, ACHE, NANP KMT2A 2020/4885MEN1 4791/4885SMN1; SMN2 2060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.