Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11957888 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL23017120 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL29556081 | 0.79 | CYP3A4 (0.36) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL309832 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL202288 | 0.77 | ALDH1A1 (0.69) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL20925070 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPTLMNANPSR1SMN1; SMN2 | |
| SCHEMBL14088888 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL3966378 | 0.74 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL2999328 | 0.74 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL17203652 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120252777-A1 | THIAZOLOPYRIMIDINE COMPOUNDS | HOFFMANN-LA ROCHE INC. | 2012-10-04 | — | — | US | disclosed |
| US-20120115811-A1 | PHENYLANALINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | AMGEN INC. (US) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115811-A1 | PHENYLANALINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | IAPP, INSR, AMY2A | ALDH1A1 2340/4885MAPT 4112/4885MEN1 3254/4885 |
| US-20120252777-A1 | THIAZOLOPYRIMIDINE COMPOUNDS | SYK, BTK, ZAP70 | ALDH1A1 2469/4885MAPT 3595/4885MEN1 3729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.