SCHEMBL309832

SCHEMBL309832

COc1cc(Br)cc(Br)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
CYP1A1 P04798 6/20 0.43
CYP1B1 Q16678 6/20 0.43
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA12 O43570 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CYP3A4 P08684 3/20 0.42
CYP1A2 P05177 3/20 0.39
CYP2E1 P05181 2/20 0.39
CYP2C8 P10632 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2A6 P11509 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP4B1 P13584 2/20 0.39
CYP2B6 P20813 2/20 0.39
CYP3A5 P20815 2/20 0.39
CYP2A7 P20853 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202288 0.94 ALDH1A1 (0.69) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL2999328 0.91 ALDH1A1 (0.65) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL3966378 0.91 ALDH1A1 (0.65) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL15641765 0.86 CYP1A1 (0.50) ALDH1A1CYP1A1CYP1B1CYP3A4CYP1A2
SCHEMBL388060 0.84 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL29427076 0.84 ALDH1A1 (0.48) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL422650 0.82 CYP3A4 (0.50) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL17203652 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CA1CA2
SCHEMBL14788171 0.82 ALDH1A1 (0.52) ALDH1A1CYP1A1CYP1B1CYP3A4CYP1A2
SCHEMBL1710751 0.82 ALDH1A1 (0.46) ALDH1A1CYP1A1CYP1B1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119574738-A Method for detecting related substances in trimethylphloroglucinol 河北广祥制药有限公司 2025-03-07 CN claimed
CN-116554378-A Non-metallocene catalyst, preparation method and application 万华化学集团股份有限公司 2023-08-08 CN claimed
CN-114773614-A Bimetal controllable distribution supramolecular material and preparation method thereof 吉林大学 2022-07-22 CN claimed
CN-103193784-B A kind of containing pyrimidine group rigidity Conjugate macrocycle compound and its preparation method and application DONGHUA UNIVERSITY (CN) 2015-10-28 CN claimed
US-12637483-B2 Fused polycyclic compound and light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2026-05-26 US disclosed
US-12606741-B2 Compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2026-04-21 US disclosed
US-12588411-B2 Organic electroluminescence device and fused polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2026-03-24 US disclosed
US-12426499-B2 Organic electroluminescence device and fused polycyclic compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2025-09-23 US disclosed
EP-4108667-B1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME SFC CO LTD (KR) 2025-08-13 EP disclosed
US-20250179075-A1 MK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-06-05 US disclosed
US-20250161271-A1 PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING ANTICANCER AGENT AND NOVEL COMPOUND HAVING INHIBITORY ACTIVITY WITH RESPECT TO PROSTAGLANDIN E2 RECEPTORS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2025-05-22 US disclosed
CN-119638755-A Binuclear ruthenium pyridine coordination supermolecule self-assembled compound, and preparation method and application thereof 江苏师范大学 2025-03-18 CN disclosed
EP-0650476-B1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMA CO LTD (JP) 2002-06-26 EP disclosed
US-6136826-A AMINOPIPERIDINE COMPOUNDS SUBSTITUTED WITH ALKANOYL OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2000-10-24 US disclosed
US-5760058-A Peripheral vasodilating agent containing piperidine derivative as active ingredient OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-06-02 US disclosed
US-5656642-A Peripheral vasodilating agent containing piperidine derivative as active ingredient OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-08-12 US disclosed
EP-0650476-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-05-03 EP disclosed
WO-1994022826-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-13 WO disclosed
US-4135045-A PROCESS FOR POLYMERIZATION OF OLEFINS AND CATALYST COMPOSITION THEREFOR MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1979-01-16 US disclosed
US-4048415-A TITANIUM-ALUMINUM COORDINATION CATALYSTS MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1977-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606741-B2 Compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device CRY1, CRY2, CYBA ALDH1A1 21/4885CYP1A1 8/4885CYP1B1 9/4885
US-12637483-B2 Fused polycyclic compound and light emitting device including the same ESR2, EMC2, CRY2 ALDH1A1 755/4885CYP1A1 165/4885CYP1B1 126/4885
US-20250161271-A1 PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING ANTICANCER AGENT AND NOVEL COMPOUND HAVING INHIBITORY ACTIVITY WITH RESPECT TO PROSTAGLANDIN E2 RECEPTORS PTGES2, PTGIR, PTGES ALDH1A1 613/4885CYP1A1 672/4885CYP1B1 1218/4885
US-12588411-B2 Organic electroluminescence device and fused polycyclic compound for organic electroluminescence device LEF1, CCNL2, LAS1L ALDH1A1 429/4885CYP1A1 205/4885CYP1B1 360/4885
US-20250179075-A1 MK2 DEGRADERS AND USES THEREOF MKNK2, MKRN3, DUS2 ALDH1A1 2904/4885CYP1A1 1580/4885CYP1B1 963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.