SCHEMBL60313

SCHEMBL60313

[O]c1ccccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 2/20 0.48
HPGD P15428 1/20 0.48
BCL2L1 Q07817 1/20 0.48
CYP2A6 P11509 1/20 0.48
MAPK1 P28482 1/20 0.48
HDAC4 P56524 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
BCAT2 O15382 1/20 0.44
BACE1 P56817 1/20 0.43
PTGS2 P35354 1/20 0.43
DPP4 P27487 1/20 0.42
MGLL Q99685 1/20 0.41
HNF4A P41235 1/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9937968 0.95 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL11898487 0.94 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL223708 0.92 PTGS2 (0.46) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL9936642 0.83 PTGER1 (0.49) ALDH1A1HDAC4HDAC2HDAC8MGLL
SCHEMBL715213 0.81 MEN1 (0.47) ALDH1A1HPGDMAPK1TDP1BACE1
SCHEMBL10988620 0.79 PTGS2 (0.52) ALDH1A1HSD17B10HPGDCYP2A6PTGS2
SCHEMBL28317839 0.79 PTGS2 (0.52) ALDH1A1BCL2L1PTGS2SMN1; SMN2MAPT
SCHEMBL283139 0.79 HNF4A (0.45) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL7182219 0.79 MEN1 (0.44) ALDH1A1HPGDMAPK1TDP1PTGS2
SCHEMBL314438 0.79 CYP3A4 (0.50) ALDH1A1HSD17B10HPGDMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5173 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115678464-B Adhesive film, optical member including the same, and optical display apparatus including the same 三星SDI株式会社 2024-05-28 CN claimed
CN-118019810-A Combinations of specific fused naphthopyran isomers 罗登斯托克有限责任公司 2024-05-10 CN claimed
US-11965102-B2 Photochromic annelated naphthopyrane systems with special substituents, for attaining rapid lightening speeds RODENSTOCK GMBH (DE) 2024-04-23 US claimed
CN-117831652-A Prediction method of olefin hydroformylation positive-to-negative ratio 上海华谊控股集团有限公司 2024-04-05 CN claimed
CN-110462514-B Photosensitive resin composition, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2023-12-15 CN claimed
CN-112424180-B Photochromic fused naphthopyran systems with specific substituents for obtaining high lightening speeds 罗登斯托克有限责任公司 2023-12-08 CN claimed
EP-4240797-A1 COMBINATION OF SPECIFIC ANNELLATED NAPHTHOPYRANE ISOMERS Rodenstock GmbH (DE) 2023-09-13 EP claimed
CN-111527636-B Electrolyte for nonaqueous electrolyte battery and nonaqueous electrolyte battery using same 中央硝子株式会社 2023-08-15 CN claimed
US-20230235217-A1 LUMINESCENT COMPOUND, METHOD FOR PRODUCING LUMINESCENT COMPOUND, LUMINESCENT COMPOSITION, LUMINESCENT THIN FILM AND LUMINESCENT PARTICLES Konica Minolta, Inc. (JP) 2023-07-27 US claimed
WO-2023135127-A1 COMBINATION OF SPECIFIC ANNELLATED NAPHTHOPYRANE ISOMERS RODENSTOCK GMBH (DE) 2023-07-20 WO claimed
EP-0180313-A1 Triazole or imidazole fungicide compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-05-07 EP claimed
EP-0162383-A1 Biologically active agent containing substituted isoxazolidines, isoxazolidines and their preparation BAYER AG (DE) 1985-11-27 EP claimed
EP-0074170-B1 CHROMAN COMPOUNDS, PROCESS FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1985-10-16 EP claimed
US-4537974-A Diethynylated phenylbenzimidazole compounds HUGHES AIRCRAFT COMPANY (US) 1985-08-27 US claimed
EP-0042569-A1 4,4-Disubstituted spiro-1,4-dihydropyridines, process for producing them and their use as intermediates BAYER AG (DE) 1981-12-30 EP claimed
US-4307110-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1981-12-22 US claimed
US-4211677-A Polyphosphazene copolymers with phenoxy and with phenylphenoxy and/or naphthoxy groups, and aqueous dispersions DESOTO, INC. (US) 1980-07-08 US claimed
EP-0009482-A1 POLYPHOSPHAZENE AQUEOUS SUSPENSIONS AND HALOGEN-FREE COPOLYMERS USEFUL THEREIN ROSE, Selwyn, H. (US) 1980-04-16 EP claimed
WO-1979000367-A1 POLYPHOSPHAZENE AQUEOUS SUSPENSIONS AND HALOGEN-FREE COPOLYMERS USEFUL THEREIN ROSE S 1979-06-28 WO claimed
US-3948877-A POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US claimed