SCHEMBL715213

SCHEMBL715213

[O]c1ccccc1-c1ccccc1[O]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
CDC25B P30305 3/20 0.47
MAOA P21397 3/20 0.44
MAPK1 P28482 3/20 0.44
POLB P06746 3/20 0.44
S100A4 P26447 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
APAF1 O14727 2/20 0.44
TDP2 O95551 2/20 0.44
RECQL P46063 2/20 0.44
NPC1 O15118 2/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
CES1 P23141 2/20 0.44
RAB9A P51151 2/20 0.44
BLM P54132 2/20 0.44
CES2 O00748 1/20 0.44
TERT O14746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6237504 0.83 ALDH1A1 (0.50) MEN1KMT2AMAOAMAPK1POLB
SCHEMBL11750730 0.83 CYP2A6 (0.50) MEN1KMT2AMAPK1POLBSMN1; SMN2
SCHEMBL3568990 0.83 TSHR (0.45) MEN1KMT2ASMN1; SMN2APAF1TDP2
SCHEMBL60313 0.81 ALDH1A1 (0.48) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL11898487 0.81 ALDH1A1 (0.42) MEN1KMT2ACDC25BMAOAMAPK1
SCHEMBL446264 0.79
SCHEMBL298203 0.79 PTPN1 (0.46) POLBKDM4ETDP1DNMT1ALDH1A1
SCHEMBL3563147 0.79 CSNK2A2 (0.44) MAPK1SMN1; SMN2NPC1LMNAMAPT
SCHEMBL4398782 0.77 CA1 (0.52) MEN1KMT2ACDC25BPOLBSMN1; SMN2
SCHEMBL9937968 0.76 ALDH1A1 (0.47) MEN1KMT2AMAPK1SMN1; SMN2APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365523-A1 PROCESS FOR PREPARING 3-(CYCLOHEX-1-EN-1-YL)PROPANAL DERIVATIVES FIRMENICH SA (CH) 2023-11-16 US disclosed
WO-2023166005-A1 PROCESS FOR PREPARING UNSATURATED ALDEHYDES FIRMENICH SA (CH) 2023-09-07 WO disclosed
EP-4153552-A2 PROCESS AND INTERMEDIATES FOR PREPARING 3-(CYCLOHEX-1-EN-1-YL) PROPANAL DERIVATIVES Firmenich SA (CH) 2023-03-29 EP disclosed
US-8357765-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-22 US disclosed
US-20120264889-A1 PRODUCTION PROCESS OF OLEFIN POLYMERIZATION CATALYST AND OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-18 US disclosed
US-8288490-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
US-8188202-B2 Making polymers based on monomer 9,9-Diallylfluorene; diallyl groups form cyclohexane ring upon polymerization; superior heat resistance; use of diimine-based nickel complex catalyst, organoaluminum, and boron compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-29 US disclosed
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed
US-20120053311-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed
US-7799886-B2 Diene polymer and production process thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-21 US disclosed
US-20090221774-A1 DIENE POLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-09-03 US disclosed
US-20090036696-A1 IRIDIUM COMPLEXES TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-02-05 US disclosed
US-6472345-B2 TITANIUM HALIDES, SULFONATES OR DIOLATES SOLVIAS AG (CH) 2002-10-29 US disclosed
US-6369257-B1 COMPLEXING RHODIUM BISPHOSPHITE HYDROFORMYLATION CATALYST ON SUPPORT E. I. DU PONT DE NEMOURS AND COMPANY 2002-04-09 US disclosed
US-20020026067-A1 Catalytic halogenation of activated methylene and methine compounds SOLVIAS AG (CH) 2002-02-28 US disclosed
EP-1151980-A1 Catalytic halogenation of activated methylene and methine compound Solvias AG (CH) 2001-11-07 EP disclosed
EP-1082285-A1 HYDROFORMYLATION OF OLEFINS USING SUPPORTED BIS(PHOSPHORUS) LIGANDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-03-14 EP disclosed
WO-1999062855-A1 HYDROFORMYLATION OF OLEFINS USING SUPPORTED BIS(PHOSPHORUS) LIGANDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-12-09 WO disclosed
US-4061617-A ANTIOXIDANT, DIELECTRIC STABILIZERS, SEMICONDUCTORS, ION EXCHANGE RESINS GENERAL ELECTRIC COMPANY (US) 1977-12-06 US disclosed
US-3959223-A Oxidation-reduction diphenoquinone-diphenonhydroquinone polymers GENERAL ELECTRIC COMPANY (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036696-A1 IRIDIUM COMPLEXES HAX1, MLX, H1-0 MEN1 1399/4885KMT2A 2830/4885CDC25B 1524/4885
US-20020026067-A1 Catalytic halogenation of activated methylene and methine compounds TET1, TPO, EMG1 MEN1 1031/4885KMT2A 537/4885CDC25B 1716/4885
US-20230365523-A1 PROCESS FOR PREPARING 3-(CYCLOHEX-1-EN-1-YL)PROPANAL DERIVATIVES CYP1A1, CYP51A1, HPD MEN1 3898/4885KMT2A 4682/4885CDC25B 1036/4885
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION PPOX, SOD1, AP1M1 MEN1 2714/4885KMT2A 2207/4885CDC25B 2961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.