Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030958 | 0.88 | MAPK1 (0.37) | S1PR1S1PR3MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6480485 | 0.88 | SMN1; SMN2 (0.37) | S1PR1S1PR3MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6029698 | 0.85 | KMT2A (0.52) | MAPK1ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3457566 | 0.85 | S1PR3 (0.40) | S1PR1S1PR3S1PR2KMT2ABDKRB1 | |
| SCHEMBL6031138 | 0.81 | MEN1 (0.41) | S1PR1S1PR3S1PR2KMT2AMEN1 | |
| SCHEMBL3457836 | 0.80 | PTGER4 (0.43) | S1PR1S1PR3ALDH1A1KMT2ACNR1 | |
| SCHEMBL6029625 | 0.74 | KMT2A (0.43) | MAPK1ALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL6905404 | 0.72 | TAAR1 (0.43) | MAPK1ALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL68154 | 0.70 | SLC6A9 (0.38) | S1PR1S1PR3MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL6489914 | 0.70 | SLC6A9 (0.38) | MAPK1KMT2AP2RX3P2RX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074742-B2 | Pyridinyl amides and imides for use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-07-11 | — | — | US | claimed |
| US-20040044040-A1 | Pyridinyl amides and imides for use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-03-04 | — | — | US | claimed |
| EP-1322614-A2 | PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES | E. I. du Pont de Nemours and Company (US) | 2003-07-02 | — | — | EP | claimed |
| WO-2002022583-A2 | PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-03-21 | — | — | WO | claimed |
| US-7074742-B2 | Pyridinyl amides and imides for use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-07-11 | — | — | US | disclosed |
| US-20050020643-A1 | Pyridinyl amides and compositions thereof for use as fungicides | E.I. DU PONT DE NEMOURS AND COMPANY | 2005-01-27 | — | — | US | disclosed |
| EP-1485355-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040044040-A1 | Pyridinyl amides and imides for use as fungicides | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-03-04 | — | — | US | disclosed |
| WO-2003080576-A2 | PYRIDINYL AMIDES AND COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |
| EP-1322614-A2 | PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES | E. I. du Pont de Nemours and Company (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002022583-A2 | PYRIDINYL AMIDES AND IMIDES FOR USE AS FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044040-A1 | Pyridinyl amides and imides for use as fungicides | CBR1, CBR3, AOC3 | S1PR1 475/4885S1PR3 449/4885MAPK1 1077/4885 |
| US-20050020643-A1 | Pyridinyl amides and compositions thereof for use as fungicides | ME3, CYC1, ME2 | S1PR1 1173/4885S1PR3 1667/4885MAPK1 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.