Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13851819 | 1.00 | ALOX5 (0.44) | ALOX5ESR1ESR2MAPK1ALDH1A1 | |
| SCHEMBL13851823 | 0.92 | ALDH1A1 (0.41) | ALOX5ESR1ESR2MAPK1ALDH1A1 | |
| SCHEMBL6031344 | 0.87 | ESR1 (0.50) | ALOX5ESR1ESR2MAPK1MEN1 | |
| SCHEMBL6030742 | 0.87 | ESR1 (0.50) | ALOX5ESR1ESR2MAPK1MEN1 | |
| SCHEMBL15147215 | 0.83 | ESR1 (0.53) | ALOX5ESR1ESR2HPGDMEN1 | |
| SCHEMBL18913903 | 0.81 | SMN1; SMN2 (0.57) | ALOX5ESR1ESR2MAPK1ALDH1A1 | |
| SCHEMBL13851801 | 0.81 | HSD17B1 (0.40) | ALOX5ESR1ESR2ALDH1A1HPGD | |
| SCHEMBL13851810 | 0.81 | HSD17B1 (0.40) | ALOX5ESR1ESR2ALDH1A1HPGD | |
| SCHEMBL29625130 | 0.78 | NPC1 (0.52) | ALOX5ESR1ESR2ALDH1A1HPGD | |
| SCHEMBL547889 | 0.78 | NPC1 (0.52) | ALOX5ESR1ESR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586735-B2 | Hydroxyphenyl triazines with an aromatic carbocyclic fused ring system | BASF SE (DE) | 2013-11-19 | — | — | US | disclosed |
| EP-1888539-B1 | HYDROXYPHENYLTRIAZINES WITH AN AROMATIC CARBOCYCLIC FUSED RING SYSTEM | BASF SE (DE) | 2013-09-18 | — | — | EP | disclosed |
| US-20130143051-A1 | HYDROXYPHENYL TRIAZINES WITH AN AROMATIC CARBOCYCLIC FUSED RING SYSTEM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2013-06-06 | — | — | US | disclosed |
| US-20130143051-A1 | HYDROXYPHENYL TRIAZINES WITH AN AROMATIC CARBOCYCLIC FUSED RING SYSTEM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2013-06-06 | — | — | US | disclosed |
| US-8389719-B2 | Hydroxyphenyltriazines with an aromatic carbocyclic fused ring system | CIBA SPECIALTY CHEMICALS CORP. (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389719-B2 | Hydroxyphenyltriazines with an aromatic carbocyclic fused ring system | CIBA SPECIALTY CHEMICALS CORP. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20090136768-A1 | Hydroxyphenyltriazines With An Aromatic Carbocyclic Fused Ring System | CIBA CORPORATION | 2009-05-28 | — | — | US | disclosed |
| US-20090136768-A1 | Hydroxyphenyltriazines With An Aromatic Carbocyclic Fused Ring System | CIBA CORPORATION | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136768-A1 | Hydroxyphenyltriazines With An Aromatic Carbocyclic Fused Ring System | AHR, PAH, TPH2 | ALOX5 2501/4885ESR1 1525/4885ESR2 2151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.