Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.36 |
| ▸ | USP2 | O75604 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.33 |
| ▸ | GLA | P06280 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL603193 | 0.78 | KMO (0.44) | ALDH1A1CYP1A2CYP2C19USP2CYP3A4 | |
| SCHEMBL603190 | 0.76 | L3MBTL1 (0.33) | ALDH1A1CYP1A2USP2ALOX15HSD17B10 | |
| SCHEMBL18107 | 0.73 | CA2 (0.39) | — | |
| SCHEMBL602808 | 0.71 | — | — | |
| SCHEMBL601160 | 0.69 | ELANE (0.30) | — | |
| SCHEMBL601169 | 0.67 | SLC6A2 (0.37) | ALDH1A1CYP1A2CYP2C19USP2CYP3A4 | |
| SCHEMBL603109 | 0.67 | KMO (0.51) | ALDH1A1CYP1A2CYP2C19USP2CYP3A4 | |
| SCHEMBL2340433 | 0.65 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL2337221 | 0.64 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP2C19LMNAMEN1 | |
| SCHEMBL603202 | 0.64 | AR (0.37) | ALDH1A1CYP1A2CYP2C19USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432780-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| WO-2010134478-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041009-A1 | PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL | TYMP, DPYD, TYMS | ALDH1A1 2299/4885CYP1A2 912/4885CYP2C19 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.