SCHEMBL603196

SCHEMBL603196

Cc1nc(OCc2ccccc2)cc(-c2noc(=O)[nH]2)n1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.41
PLA2G10 O15496 2/20 0.41
BPGM P07738 1/20 0.40
ALDH1A1 P00352 1/20 0.39
NUDT1 P36639 1/20 0.38
XDH P47989 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
PKM P14618 1/20 0.37
BRD4 O60885 1/20 0.37
ELANE P08246 1/20 0.36
PDE2A O00408 1/20 0.36
GABRA5 P31644 1/20 0.36
PLA2G1B P04054 1/20 0.36
PLA2G5 P39877 1/20 0.36
KMO O15229 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL603195 0.80 PKM (0.40) ALDH1A1NUDT1XDHHCAR2PKM
SCHEMBL602046 0.80 POLB (0.46) PLA2G2ABPGMALDH1A1KMO
SCHEMBL601129 0.77 KMO (0.44) ALDH1A1XDHKMO
SCHEMBL607647 0.74 KMO (0.41) BPGMALDH1A1PKMKMO
SCHEMBL603096 0.73 KMO (0.40) ALDH1A1PKMKMO
SCHEMBL603696 0.71 NUDT1 (0.48) ALDH1A1NUDT1PKMPDE2A
SCHEMBL601047 0.71 DHODH (0.49) KMO
SCHEMBL603320 0.71 KMO (0.46) ALDH1A1KMO
SCHEMBL6767397 0.70 KDM4C (0.45) PLA2G2APLA2G10ALDH1A1XDHHCAR2
SCHEMBL603947 0.70 KMO (0.47) BPGMALDH1A1KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2432780-A1 PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL Sumitomo Chemical Company, Limited (JP) 2012-03-28 EP disclosed
US-20120041009-A1 PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed
US-20120041009-A1 PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed
US-20120041009-A1 PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed
WO-2010134478-A1 PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-25 WO disclosed
WO-2010134478-A1 PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120041009-A1 PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL TYMP, DPYD, TYMS PLA2G2A 2046/4885PLA2G10 2147/4885BPGM 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.