SCHEMBL6767397

SCHEMBL6767397

O=c1[nH]c(OCc2ccccc2)no1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.45
ELANE P08246 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
MAOA P21397 3/20 0.43
MAOB P27338 3/20 0.43
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NSD2 O96028 1/20 0.41
ABL1 P00519 1/20 0.41
PPARG P37231 1/20 0.41
RIN1 Q13671 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
HTT P42858 1/20 0.41
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
PLA2G10 O15496 1/20 0.40
PLA2G2A P14555 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16910470 0.71 KDM4C (0.49) KDM4CELANEHCAR2MAOAMAOB
SCHEMBL11838787 0.70 PLA2G2A (0.54) PLA2G2AGAA
SCHEMBL26162722 0.70 ALDH1A1 (0.51) L3MBTL1PLA2G10PLA2G2AXDHALDH1A1
SCHEMBL20769192 0.70 KDM4C (0.51) KDM4CELANEHCAR2MAOAMAOB
SCHEMBL22481024 0.69 PLA2G2A (0.49) PLA2G10PLA2G2AALDH1A1MMP1MMP2
SCHEMBL21028577 0.69 KDM4C (0.50) KDM4CELANEHCAR2MAOAMAOB
SCHEMBL11602358 0.68 KDM4C (0.52) KDM4CELANEHCAR2MAOAMAOB
SCHEMBL6473755 0.68 KDM4C (0.75) KDM4CELANEHCAR2MAOB
SCHEMBL28135739 0.68 KDM4C (0.52) KDM4CELANEHCAR2MAOAMAOB
SCHEMBL6765408 0.66 PKM (0.49) ELANEMAOAMAOBLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063581-A1 Herbicidal oxadiazolidines THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-04-01 US disclosed
EP-1147096-A1 HERBICIDAL OXADIAZOLIDINES E. I. du Pont de Nemours and Company (US) 2001-10-24 EP disclosed
WO-2000043377-A1 HERBICIDAL OXADIAZOLIDINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063581-A1 Herbicidal oxadiazolidines XDH, CBR3, CYP4X1 KDM4C 1024/4885ELANE 4407/4885HCAR2 2295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.