Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.59 |
| ▸ | CA2 | P00918 | 7/20 | 0.59 |
| ▸ | CA9 | Q16790 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | MMP16 | P51512 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385340 | 1.00 | CA1 (0.59) | CA1CA2CA9LMNAPOLB | |
| SCHEMBL15690459 | 0.79 | MAPT (0.48) | CA1CA2CA9LMNAPOLB | |
| SCHEMBL10674689 | 0.76 | CA1 (0.54) | CA1CA2CA9LMNAHTT | |
| SCHEMBL6553709 | 0.76 | HTT (0.64) | LMNAPOLBHTTGAATDP1 | |
| SCHEMBL27805191 | 0.75 | CA1 (1.00) | CA1CA2CA9CA5APRMT5 | |
| SCHEMBL30202428 | 0.75 | CA1 (0.73) | CA1CA2CA9LMNACA5A | |
| SCHEMBL14794997 | 0.75 | CA1 (0.54) | CA1CA2CA9LMNAPOLB | |
| SCHEMBL10435055 | 0.74 | CA2 (0.71) | CA1CA2CA9POLBCA5A | |
| SCHEMBL8971757 | 0.73 | CA1 (0.52) | CA1CA2CA9LMNAHTT | |
| SCHEMBL10678250 | 0.73 | ALDH1A1 (0.57) | CA1CA2CA9POLBCA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982281-B1 | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs | LIPOCINE INC (US) | 2006-01-03 | — | — | US | disclosed |
| US-20050171193-A1 | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs | LIPOCINE, INC. | 2005-08-04 | — | — | US | disclosed |
| WO-2004087052-A2 | OIL-CONTAINING, ORALLY ADMINISTRABLE PHARMACEUTICAL COMPOSITION FOR IMPROVED DELIVERY OF A THERAPEUTIC AGENT | LIPOCINE, INC. (US) | 2004-10-14 | — | — | WO | disclosed |
| US-20030235595-A1 | Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent | LIPOCINE, INC. | 2003-12-25 | — | — | US | disclosed |
| WO-2002039983-A2 | PHARMACEUTICAL COMPOSITIONS AND DOSAGE FORMS FOR ADMINISTRATION OF HYDROPHOBIC DRUGS | LIPOCINE, INC. (US) | 2002-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171193-A1 | Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs | LIPC, TTPA, LIPA | CA1 3419/4885CA2 2296/4885CA9 2810/4885 |
| US-20030235595-A1 | Oil-containing, orally administrable pharmaceutical composition for improved delivery of a therapeutic agent | LIPA, LIPC, CETP | CA1 4489/4885CA2 3660/4885CA9 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.