Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 12/20 | 0.53 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254244 | 0.86 | AOC3 (0.50) | HSD17B2AOC3ABHD6MGLL | |
| SCHEMBL18664587 | 0.86 | MTOR (0.44) | HSD17B1HSD17B2 | |
| SCHEMBL16942777 | 0.85 | HSD17B2 (0.53) | HSD17B1HSD17B2 | |
| SCHEMBL2229917 | 0.82 | MTOR (0.48) | — | |
| SCHEMBL5374253 | 0.81 | HSD17B1 (0.65) | HSD17B1HSD17B2AOC3ABHD6 | |
| SCHEMBL11372012 | 0.80 | AOC3 (0.82) | AOC3 | |
| SCHEMBL6184972 | 0.80 | ABHD6 (0.47) | AOC3ABHD6MGLL | |
| SCHEMBL30264842 | 0.80 | HSP90AA1 (0.49) | HSD17B1HSD17B2AOC3ABHD6MGLL | |
| SCHEMBL1831339 | 0.80 | GLS (0.50) | AOC3ABHD6MGLL | |
| SCHEMBL7021352 | 0.80 | GLS (0.53) | AOC3ABHD6MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125869-B2 | Polycyclic compounds which modulate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2006-10-24 | — | — | US | disclosed |
| EP-1572629-A1 | COMPOUNDS WHICH MODULATE PPARϝ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004052840-A1 | COMPOUNDS WHICH MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-24 | — | — | WO | disclosed |