Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 16/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254244 | 0.84 | AOC3 (0.50) | ABHD6AOC3MGLL | |
| SCHEMBL6032489 | 0.80 | HSD17B1 (0.57) | ABHD6AOC3MGLL | |
| SCHEMBL6478826 | 0.80 | PTGES (0.38) | ABHD6AOC3 | |
| SCHEMBL6184965 | 0.80 | CTSB (0.38) | AOC3 | |
| SCHEMBL6184968 | 0.80 | CTSB (0.38) | AOC3 | |
| SCHEMBL6182810 | 0.78 | AOC3 (0.47) | AOC3 | |
| SCHEMBL6184145 | 0.76 | PRMT6 (0.49) | AOC3 | |
| SCHEMBL6184148 | 0.76 | PRMT6 (0.49) | AOC3 | |
| SCHEMBL14987121 | 0.74 | GLS (0.56) | ABHD6AOC3GLS | |
| SCHEMBL6472820 | 0.72 | AOC3 (0.49) | ABHD6AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-B1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2005-06-08 | — | — | EP | disclosed |
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |