Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 5/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7269445 | 0.90 | DNM1 (0.42) | DNM1LPAR1LPAR3CA1CA2 | |
| SCHEMBL10427412 | 0.90 | DNM1 (0.42) | DNM1LPAR1LPAR3SMPD1 | |
| SCHEMBL5961097 | 0.88 | OPRM1 (0.38) | DNM1SMPD1CA1 | |
| SCHEMBL9736432 | 0.87 | HTT (0.40) | DNM1LPAR1LPAR3SMPD1LPAR2 | |
| SCHEMBL6030032 | 0.87 | LMNA (0.36) | — | |
| SCHEMBL5961136 | 0.85 | ALOX5 (0.33) | DNM1SMPD1CA1CA2 | |
| SCHEMBL15522266 | 0.85 | DNM1 (0.48) | DNM1LPAR1LPAR3SMPD1CA1 | |
| SCHEMBL11108585 | 0.85 | DNM1 (0.48) | DNM1LPAR1LPAR3SMPD1CA1 | |
| SCHEMBL2670811 | 0.85 | DNM1 (0.48) | DNM1LPAR1LPAR3CA1CA2 | |
| SCHEMBL4309898 | 0.85 | DNM1 (0.48) | DNM1LPAR1LPAR3SMPD1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666473-A1 | CARBOXYLIC ACID COMPOUNDS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-07 | — | — | EP | disclosed |