Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 14/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033984 | 0.78 | TGM2 (1.00) | TGM2 | |
| SCHEMBL6034368 | 0.76 | TGM2 (0.66) | TGM2 | |
| SCHEMBL6033379 | 0.76 | TGM2 (0.73) | TGM2KMT2AMEN1HSD17B10POLB | |
| SCHEMBL6034980 | 0.76 | TGM2 (0.65) | TGM2ALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL6034873 | 0.74 | TGM2 (0.68) | TGM2KDM4ETSHRMAPK1 | |
| SCHEMBL6034183 | 0.74 | TGM2 (0.56) | TGM2ALDH1A1HSD17B10KDM4EPOLB | |
| SCHEMBL6034054 | 0.71 | TGM2 (0.66) | TGM2MAPTNPSR1 | |
| SCHEMBL6033946 | 0.70 | TGM2 (0.68) | TGM2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6034240 | 0.69 | TGM2 (0.68) | TGM2ALDH1A1POLBMAPT | |
| SCHEMBL6034427 | 0.68 | TGM2 (0.65) | TGM2ALDH1A1HSD17B10MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060702-A1 | SUBSTITUED 3,4-DIHYDROTHIENO [2,3-D] PYRMIDINES AS TISSUE TRANSGLUTAMINASE INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-06-08 | — | — | WO | disclosed |