Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 16/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034427 | 0.87 | TGM2 (0.65) | TGM2ALDH1A1HTTMAPTLMNA | |
| SCHEMBL6034873 | 0.86 | TGM2 (0.68) | TGM2 | |
| SCHEMBL6034980 | 0.82 | TGM2 (0.65) | TGM2ALDH1A1HTTPOLBMAPT | |
| SCHEMBL6034244 | 0.81 | TGM2 (1.00) | TGM2 | |
| SCHEMBL6034054 | 0.80 | TGM2 (0.66) | TGM2HTTMAPTLMNA | |
| SCHEMBL6033990 | 0.78 | TGM2 (0.61) | TGM2ALDH1A1HTTPOLBMAPT | |
| SCHEMBL6034368 | 0.75 | TGM2 (0.66) | TGM2 | |
| SCHEMBL6033358 | 0.69 | TGM2 (0.53) | TGM2ALDH1A1HTTMAPT | |
| SCHEMBL6033982 | 0.69 | TGM2 (0.64) | TGM2ALDH1A1POLBMAPT | |
| SCHEMBL6033372 | 0.67 | TGM2 (0.60) | TGM2ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060702-A1 | SUBSTITUED 3,4-DIHYDROTHIENO [2,3-D] PYRMIDINES AS TISSUE TRANSGLUTAMINASE INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-06-08 | — | — | WO | disclosed |