Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE1A | P54750 | 2/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035364 | 0.84 | ALDH1A1 (0.32) | ALDH1A1LMNAHTR1DHTR1BCYP2A6 | |
| SCHEMBL6035817 | 0.81 | ACHE (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6035878 | 0.80 | NAMPT (0.41) | HTR1DHTR1BNAMPTPDE5APDE4A | |
| SCHEMBL6034969 | 0.76 | LMNA (0.45) | ALDH1A1LMNAPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL6034128 | 0.75 | KDM4E (0.41) | ALDH1A1LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL6607970 | 0.74 | NAMPT (0.38) | HTR1DHTR1BNAMPTPDE5APDE4A | |
| SCHEMBL6034834 | 0.73 | LMNA (0.55) | ALDH1A1LMNAHTR1DHTR1BCYP2A6 | |
| SCHEMBL6034096 | 0.72 | CYP2A6 (0.44) | ALDH1A1LMNAHTR1DHTR1BCYP2A6 | |
| SCHEMBL6606922 | 0.69 | HTR1D (0.33) | ALDH1A1HTR1DHTR1BNAMPTPDE5A | |
| SCHEMBL6633082 | 0.67 | NAMPT (0.40) | LMNANAMPTNR1I3PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052396-A1 | Arylamines for the treatment of conditions associated with gsk-3 | ASTRAZENECA (SE) | 2006-03-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052396-A1 | Arylamines for the treatment of conditions associated with gsk-3 | GSK3A, GSK3B, PYGL | ALDH1A1 2625/4885LMNA 114/4885CHRM2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.