Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6035986 | 0.98 | CYP1A2 (0.52) | CYP1A2L3MBTL1KMT2APOLBGAA | |
| SCHEMBL11230225 | 0.88 | CYP1A2 (0.47) | CYP1A2L3MBTL1KMT2APOLBGAA | |
| SCHEMBL29226009 | 0.86 | CYP1A2 (0.54) | CYP1A2L3MBTL1KMT2APOLBGAA | |
| SCHEMBL12510627 | 0.86 | GABRP (0.54) | CYP1A2L3MBTL1KMT2APOLBGAA | |
| Hydrochloric Acid SCHEMBL10659922 | 0.85 | CYP1A2 (0.44) | CYP1A2L3MBTL1KMT2APOLBGAA | |
| SCHEMBL27516639 | 0.84 | CYP1A2 (0.52) | CYP1A2L3MBTL1KMT2APOLBGAA | |
| Hydrochloric Acid SCHEMBL29076059 | 0.84 | GABRP (0.52) | CYP1A2L3MBTL1KMT2APOLBGAA | |
| SCHEMBL27515951 | 0.84 | CYP1A2 (0.52) | CYP1A2L3MBTL1KMT2APOLBGAA | |
| SCHEMBL7356567 | 0.84 | CYP1A2 (0.52) | CYP1A2L3MBTL1KMT2APOLBGAA | |
| SCHEMBL573710 | 0.83 | L3MBTL1 (0.53) | CYP1A2L3MBTL1KMT2APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087214-B2 | Water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases | ZENTARIS GMBH (DE) | 2006-08-08 | — | — | US | disclosed |
| EP-1470139-A2 | NOVEL, WATER−SOLUBLE PORPHYRIN PLATINUM COMPOUNDS WITH HIGH TUMOR SELECTIVITY AND THEIR USE FOR THE TREATMENT OF BENIGN AND MALIGNANT TUMOR DISEASES | Zentaris GmbH (DE) | 2004-10-27 | — | — | EP | disclosed |
| US-20040023942-A1 | Novel, water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases | ZENTARIS GMBH (DE) | 2004-02-05 | — | — | US | disclosed |
| WO-2003064424-A2 | WATER-SOLUBLE PORPHYRIN PLATINUM COMPOUNDS WITH HIGH TUMOR SELECTIVITY AND THEIR USE FOR THE TREATMENT OF BENIGN AND MALIGNANT TUMOR DISEASES | ZENTARIS GMBH (DE) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023942-A1 | Novel, water-soluble porphyrin platinum compounds with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases | PPOX, VHL, SLC40A1 | CYP1A2 3611/4885L3MBTL1 2285/4885KMT2A 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.