Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 5/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036512 | 0.90 | MMP2 (0.51) | TP53MEN1KMT2AMMP13EPHX2 | |
| SCHEMBL6035783 | 0.90 | MMP13 (0.58) | MMP13MMP12EPHX2MMP14MMP2 | |
| SCHEMBL6948792 | 0.81 | MMP13 (0.56) | MMP13MMP12MMP14MMP2MMP3 | |
| SCHEMBL6036011 | 0.80 | MMP13 (0.55) | TP53MMP13MMP12EPHX2MMP14 | |
| SCHEMBL6035791 | 0.80 | MMP13 (0.53) | MMP13MMP12MMP14MMP2MMP3 | |
| SCHEMBL6943119 | 0.78 | MMP13 (0.52) | MMP13MMP12MMP14MMP2RORC | |
| SCHEMBL9903075 | 0.73 | EPHX2 (0.65) | TP53MEN1KMT2AEPHX2SCN10A | |
| SCHEMBL6097841 | 0.73 | MMP13 (0.49) | TP53MEN1KMT2AMMP13MMP12 | |
| SCHEMBL29703881 | 0.72 | TP53 (0.44) | TP53MEN1KMT2AMMP13EPHX2 | |
| Hydrochloric Acid SCHEMBL29705662 | 0.72 | TP53 (0.43) | TP53MEN1KMT2AMMP13EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015234-B2 | Hydroxamic acid derivatives | CELLTECH R & D LIMITED (GB) | 2006-03-21 | — | — | US | disclosed |
| EP-1414812-B1 | HYDROXAMIC ACID DERIVATIVES | CELLTECH R&D LTD (GB) | 2006-02-22 | — | — | EP | disclosed |
| US-20040192733-A1 | Hydroxamic acid derivatives | UCB PHARMA S.A. (BE) | 2004-09-30 | — | — | US | disclosed |
| EP-1414812-A1 | HYDROXAMIC ACID DERIVATIVES | Celltech R & D Limited (GB) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003014101-A1 | HYDROXAMIC ACID DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192733-A1 | Hydroxamic acid derivatives | MMP1, MMP3, MMP13 | TP53 4696/4885MEN1 2905/4885KMT2A 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.