Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089214 | 0.85 | TSHR (0.33) | HTTALDH1A1TSHRKMT2ASLC6A2 | |
| SCHEMBL2141105 | 0.83 | TSHR (0.32) | ALDH1A1TSHRKMT2ASLC6A2SLC6A4 | |
| SCHEMBL2101604 | 0.81 | TSHR (0.33) | HTTALDH1A1TSHRKMT2ASLC6A2 | |
| SCHEMBL15842572 | 0.79 | NPBWR1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL6036795 | 0.78 | ALDH1A1 (0.32) | ALDH1A1TSHRKMT2ASLC6A2SLC6A4 | |
| SCHEMBL139764 | 0.76 | NPBWR1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL29393805 | 0.76 | NPBWR1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL31158055 | 0.76 | P2RX7 (0.39) | HTTALDH1A1TSHRSLC6A2SLC6A4 | |
| SCHEMBL11265054 | 0.76 | P2RX7 (0.39) | HTTALDH1A1TSHRSLC6A2SLC6A4 | |
| SCHEMBL893214 | 0.76 | GABRA1 (0.44) | ALDH1A1TSHRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6991852-B2 | A silica-based material that includes a silica-based substrate and a polymerized organic material disposed thereon. The polymerized organic material is made from reactive organic moieties bonded to the silica-based substrate. | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2006-01-31 | — | — | US | disclosed |
| US-20030219597-A1 | Silica-based materials and methods | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-11-27 | — | — | US | disclosed |
| WO-2003078159-A1 | SILICA-BASED MATERIALS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-09-25 | — | — | WO | disclosed |