Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716076 | 0.81 | IDO1 (0.38) | IDO1LMNASIGMAR1MEN1KMT2A | |
| SCHEMBL27646102 | 0.79 | RAB9A (0.37) | IDO1LMNAMEN1KMT2ANPC1 | |
| SCHEMBL11273214 | 0.77 | TSHR (0.47) | IDO1LMNAL3MBTL1SMN1; SMN2HRH3 | |
| SCHEMBL11269441 | 0.77 | TSHR (0.44) | IDO1LMNAL3MBTL1MAOAMEN1 | |
| SCHEMBL20658031 | 0.75 | IDO1 (0.44) | IDO1LMNAL3MBTL1SIGMAR1MEN1 | |
| SCHEMBL6036848 | 0.75 | IDO1 (0.48) | IDO1LMNAL3MBTL1SIGMAR1MAOA | |
| SCHEMBL27418301 | 0.74 | MAOA (0.47) | IDO1LMNASIGMAR1MAOASMN1; SMN2 | |
| SCHEMBL7429112 | 0.73 | IDO1 (0.55) | IDO1LMNASIGMAR1MEN1KMT2A | |
| SCHEMBL25190743 | 0.73 | IDO1 (0.55) | IDO1LMNASIGMAR1MAOAMEN1 | |
| SCHEMBL10044994 | 0.73 | IDO1 (0.55) | IDO1LMNAL3MBTL1SIGMAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332612-A | N-METHYL-2-PYRROLIDONE AND A HALOALKYL SILANE | GAF CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |