Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | MTOR | P42345 | 1/20 | 0.67 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.67 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.67 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.63 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.63 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.60 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.54 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037075 | 1.00 | LMNA (0.67) | LMNATHRBMTORMDM2NCOA1 | |
| Cytidine SCHEMBL17371752 | 0.92 | LMNA (0.80) | LMNATHRBMTORMDM2NCOA1 | |
| Cytidine SCHEMBL600535 | 0.92 | LMNA (0.80) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL14565251 | 0.90 | LMNA (0.81) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL11120331 | 0.90 | LMNA (0.81) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL14580391 | 0.90 | LMNA (0.81) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL12031031 | 0.90 | LMNA (0.81) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL30116 | 0.90 | LMNA (0.81) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL21423095 | 0.90 | LMNA (0.81) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL30115 | 0.90 | LMNA (0.81) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060036087-A1 | 2'-deoxy-2'-fluoro modified RNA | RIBOZYME PHARMACEUTICALS, INC. | 2006-02-16 | — | — | US | disclosed |
| US-6890908-B1 | Modified ribozymes | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2005-05-10 | — | — | US | disclosed |
| US-5817635-A | RNA MOLECULES WITH CATALYTIC ACTIVITY | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 1998-10-06 | — | — | US | disclosed |
| US-5698687-A | RNA MOLECULE CONTAINING MODIFIED NUCLOSIDE | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 1997-12-16 | — | — | US | disclosed |
| US-5672695-A | GENETIC ENGINEERED RNA MOLECULE, ATLEAST ONE MODIFIED NUCLEOSIDE HAVING A HALO, AMINO, MONO OR DISUBSTITUTED AMINO AND AZIDE MODIFIER GROUPS REPLACING HYDROXY GROUP AT 2' POSITION OF DRIBOSE SUGAR; SHOWS CATALYTIC ACTIVITY | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 1997-09-30 | — | — | US | disclosed |
| EP-0552178-B1 | MODIFIED RIBOZYMES | MAX PLANCK GESELLSCHAFT (DE) | 1997-01-02 | — | — | EP | disclosed |
| EP-0552178-A1 | MODIFIED RIBOZYMES. | MAX PLANCK GESELLSCHAFT (DE) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992007065-A1 | MODIFIED RIBOZYMES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 1992-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036087-A1 | 2'-deoxy-2'-fluoro modified RNA | RNGTT, NSUN2, NSUN3 | LMNA 4076/4885THRB 3468/4885MTOR 3613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.