Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037784 | 0.92 | TSHR (0.60) | CPA3FOLH1TSHRPOLB | |
| SCHEMBL5053123 | 0.89 | FOLH1 (0.61) | CPA3FOLH1GRM3 | |
| SCHEMBL6037839 | 0.87 | CPA3 (0.58) | CPA3FOLH1GRM3 | |
| SCHEMBL8060046 | 0.86 | TBXAS1 (0.51) | CPA3FOLH1 | |
| SCHEMBL7613981 | 0.83 | FOLH1 (0.49) | CPA3FOLH1GRM3 | |
| SCHEMBL2172375 | 0.81 | TSHR (0.70) | TSHRPOLB | |
| SCHEMBL7350860 | 0.81 | CPA3 (0.71) | CPA3FOLH1 | |
| SCHEMBL12145183 | 0.81 | GRM3 (0.68) | CPA3FOLH1GRM3 | |
| SCHEMBL1374848 | 0.81 | FOLH1 (0.59) | CPA3FOLH1GRM3 | |
| SCHEMBL7608702 | 0.80 | FOLH1 (0.72) | FOLH1GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999033848-B1 | PROCESS FOR PREPARING ENANTIOMER-ENRICHED HYDROXYPHOSPHINYL DERIVATIVES | GUILFORD PHARM INC (US) | 1999-08-12 | — | — | WO | claimed |
| WO-2006093991-A1 | COMPOUNDS WHICH BIND PSMA AND USES THEREOF | THE CLEVELAND CLINIC FOUNDATION (US) | 2006-09-08 | — | — | WO | disclosed |