Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CPA3 | P15088 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CETP | P11597 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037797 | 0.92 | CPA3 (0.56) | TSHRCPA3POLBFOLH1 | |
| SCHEMBL5053123 | 0.86 | FOLH1 (0.61) | CPA3FOLH1 | |
| SCHEMBL1374848 | 0.84 | FOLH1 (0.59) | CPA3FOLH1 | |
| SCHEMBL1374317 | 0.83 | FOLH1 (0.57) | TSHRCPA3FOLH1 | |
| SCHEMBL6037839 | 0.82 | CPA3 (0.58) | CPA3FOLH1 | |
| SCHEMBL2172375 | 0.79 | TSHR (0.70) | TSHRPOLBCETPMAPK1 | |
| SCHEMBL7350860 | 0.79 | CPA3 (0.71) | CPA3FOLH1MAPK1 | |
| SCHEMBL12145183 | 0.79 | GRM3 (0.68) | CPA3FOLH1 | |
| SCHEMBL8060046 | 0.79 | TBXAS1 (0.51) | CPA3FOLH1 | |
| SCHEMBL6037845 | 0.78 | NPSR1 (0.49) | TSHRCPA3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093991-A1 | COMPOUNDS WHICH BIND PSMA AND USES THEREOF | THE CLEVELAND CLINIC FOUNDATION (US) | 2006-09-08 | — | — | WO | disclosed |