Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437834 | 0.81 | ALOX15 (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2ATSHR | |
| Phosphoric Acid SCHEMBL17156463 | 0.71 | PTGS2 (0.64) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL602096 | 0.71 | PTGS2 (0.69) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL966720 | 0.69 | SRC (0.54) | TSHRCYP2C19ALOX15PGK1PGK2 | |
| Phosphoric Acid SCHEMBL27934163 | 0.69 | AKR1C3 (0.55) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL8064188 | 0.69 | PGK1 (0.40) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL8057418 | 0.69 | PTGS1 (0.45) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL10749294 | 0.68 | TSHR (0.44) | MAPTLMNARECQLKDM4EALDH1A1 | |
| Ethylene SCHEMBL28098281 | 0.67 | PTGS2 (0.69) | PTGS2PTGS1MAPTCXCR1CXCR2 | |
| SCHEMBL23581099 | 0.67 | PTGS2 (0.75) | PTGS2PTGS1MAPTCXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093991-A1 | COMPOUNDS WHICH BIND PSMA AND USES THEREOF | THE CLEVELAND CLINIC FOUNDATION (US) | 2006-09-08 | — | — | WO | disclosed |
| US-6384022-B1 | ENZYME INHIBITORS | GUILFORD PHARMACEUTICALS INC. | 2002-05-07 | — | — | US | disclosed |