Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260932 | 0.86 | MEN1 (0.41) | SMN1; SMN2LMNAHPGDMEN1KMT2A | |
| SCHEMBL6376374 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL5280748 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL5280854 | 0.72 | HDAC6 (0.56) | HDAC3HDAC1 | |
| SCHEMBL5291493 | 0.72 | POLB (0.49) | SMN1; SMN2LMNAMAPTALDH1A1MTNR1A | |
| SCHEMBL5282279 | 0.71 | ITGB3 (0.47) | LMNAHPGDKMT2AATMHDAC3 | |
| SCHEMBL6038201 | 0.71 | HDAC6 (0.54) | HDAC3HDAC1 | |
| SCHEMBL23417617 | 0.71 | ALDH1A1 (0.77) | SMN1; SMN2LMNAMEN1KMT2AMAPT | |
| SCHEMBL6038071 | 0.71 | ALDH1A1 (0.57) | MEN1KMT2AMAPTALDH1A1MTNR1A | |
| SCHEMBL7278495 | 0.70 | PLAAT3 (0.74) | SMN1; SMN2LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | SMN1; SMN2 3733/4885LMNA 851/4885HPGD 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.