Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037909 | 0.86 | SMN1; SMN2 (0.45) | MEN1KMT2AATMLMNAHPGD | |
| SCHEMBL8637193 | 0.66 | KMT2A (0.60) | MEN1KMT2ALMNASMN1; SMN2HDAC1 | |
| SCHEMBL13255493 | 0.65 | ALDH1A1 (0.62) | MEN1KMT2AHPGDSMN1; SMN2HDAC3 | |
| SCHEMBL9973826 | 0.65 | KDM4E (0.70) | KMT2ALMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2845251 | 0.65 | HCAR2 (0.71) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL23417617 | 0.65 | ALDH1A1 (0.77) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7280544 | 0.65 | ALDH1A1 (0.62) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7278495 | 0.65 | PLAAT3 (0.74) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13352155 | 0.65 | ALDH1A1 (0.71) | MEN1KMT2ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL4023394 | 0.65 | KMT2A (0.79) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |