Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038350 | 0.93 | DDR2 (0.42) | RAB9AKDM4EAOC3PDE5ASCD | |
| SCHEMBL6037944 | 0.89 | LMNA (0.48) | RAB9APDE5A | |
| SCHEMBL5280368 | 0.89 | RAB9A (0.43) | RAB9AKDM4EPDE5ASMN1; SMN2 | |
| SCHEMBL5279990 | 0.88 | ROCK2 (0.46) | RAB9APDE5ASCD | |
| SCHEMBL5282375 | 0.87 | AOC3 (0.47) | RAB9AAOC3SMN1; SMN2 | |
| SCHEMBL6037949 | 0.86 | RAB9A (0.49) | RAB9AKDM4ESMN1; SMN2RXFP1 | |
| SCHEMBL6038138 | 0.86 | MAPT (0.50) | RAB9ARXFP1 | |
| SCHEMBL5281155 | 0.85 | SMN1; SMN2 (0.51) | RAB9AKDM4ESMN1; SMN2RXFP1 | |
| SCHEMBL5281070 | 0.84 | MEN1 (0.47) | — | |
| SCHEMBL5286061 | 0.84 | ALDH1A1 (0.55) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | RAB9A 2884/4885KDM4E 67/4885AOC3 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.