Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 3/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709719 | 0.87 | ERN1 (0.46) | ALDH1A1KMT2AMEN1TDP1PADI4 | |
| SCHEMBL605657 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1TDP1PADI4 | |
| SCHEMBL15248166 | 0.85 | ERN1 (0.42) | ALDH1A1KMT2AMEN1TDP1PADI4 | |
| SCHEMBL320588 | 0.77 | GABRA1 (0.50) | ALDH1A1KMT2AMEN1TDP1PADI4 | |
| SCHEMBL16960336 | 0.75 | PDXK (0.41) | ALDH1A1LMNAKDM4EAPOBEC3GPDCD1 | |
| SCHEMBL28210797 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1TDP1PADI4 | |
| SCHEMBL2646726 | 0.74 | ERN1 (0.61) | ALDH1A1TDP1PADI4KDM4EERN1 | |
| SCHEMBL29942439 | 0.73 | LMNA (0.55) | ALDH1A1KMT2AMEN1TDP1PADI4 | |
| SCHEMBL2544808 | 0.73 | LMNA (0.55) | ALDH1A1KMT2AMEN1TDP1PADI4 | |
| SCHEMBL16951737 | 0.73 | GABRA1 (0.46) | ALDH1A1LMNAAPOBEC3GPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6861065-B2 | Method of producing intraocular lenses in vivo | ADVANCED MEDICAL OPTICS, INC. (US) | 2005-03-01 | — | — | US | claimed |
| EP-1250162-B1 | MATERIALS SUITABLE FOR INTRAOCULAR LENS PRODUCTION | PHARMACIA GRONINGEN BV (NL) | 2004-09-15 | — | — | EP | claimed |
| US-20040037867-A1 | Methods of producing intraocular lenses | ADVANCED MEDICAL OPTICS, INC. | 2004-02-26 | — | — | US | claimed |
| US-20030208268-A1 | Method of producing intraocular lenses in vivo | ADVANCED MEDICAL OPTICS, INC. | 2003-11-06 | — | — | US | claimed |
| US-6589550-B1 | Methods of producing intraocular lenses and materials suitable for their production | PHARMACIA GRONINGEN BV (NL) | 2003-07-08 | — | — | US | claimed |
| EP-1250162-A2 | METHODS OF PRODUCING INTRAOCULAR LENSES AND MATERIALS SUITABLE FOR THEIR PRODUCTION | Pharmacia & Upjohn Groningen BV (NL) | 2002-10-23 | — | — | EP | claimed |
| WO-1999047185-A2 | METHODS AND MATERIALS FOR PRODUCING INTRACULAR LENSES | PHARMACIA & UPJOHN GRONINGEN B.V. (NL) | 1999-09-23 | — | — | WO | claimed |
| US-7141248-B2 | Methods of producing intraocular lenses | AMO GRONINGEN BV (NL) | 2006-11-28 | — | — | US | disclosed |
| US-6861065-B2 | Method of producing intraocular lenses in vivo | ADVANCED MEDICAL OPTICS, INC. (US) | 2005-03-01 | — | — | US | disclosed |
| EP-1250162-B1 | MATERIALS SUITABLE FOR INTRAOCULAR LENS PRODUCTION | PHARMACIA GRONINGEN BV (NL) | 2004-09-15 | — | — | EP | disclosed |
| US-20040037867-A1 | Methods of producing intraocular lenses | ADVANCED MEDICAL OPTICS, INC. | 2004-02-26 | — | — | US | disclosed |
| US-20030208268-A1 | Method of producing intraocular lenses in vivo | ADVANCED MEDICAL OPTICS, INC. | 2003-11-06 | — | — | US | disclosed |
| US-6589550-B1 | Methods of producing intraocular lenses and materials suitable for their production | PHARMACIA GRONINGEN BV (NL) | 2003-07-08 | — | — | US | disclosed |
| EP-1250162-A2 | METHODS OF PRODUCING INTRAOCULAR LENSES AND MATERIALS SUITABLE FOR THEIR PRODUCTION | Pharmacia & Upjohn Groningen BV (NL) | 2002-10-23 | — | — | EP | disclosed |
| WO-1999047185-A2 | METHODS AND MATERIALS FOR PRODUCING INTRACULAR LENSES | PHARMACIA & UPJOHN GRONINGEN B.V. (NL) | 1999-09-23 | — | — | WO | disclosed |