Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6039434 | 0.95 | ALDH1A1 (0.34) | ALDH1A1CTSLCTSBCTSK | |
| SCHEMBL6039715 | 0.90 | MCL1 (0.31) | ALDH1A1 | |
| SCHEMBL4630957 | 0.80 | EPHX1 (0.35) | ALDH1A1BCHEOPRD1DPP4 | |
| SCHEMBL5101070 | 0.79 | FFAR1 (0.40) | L3MBTL1CTSLCTSBCTSKPOLB | |
| SCHEMBL10244794 | 0.77 | CHRNB2 (0.41) | ALDH1A1 | |
| SCHEMBL18925122 | 0.76 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1POLBBCHEOPRD1 | |
| SCHEMBL18378505 | 0.76 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1POLBBCHEOPRD1 | |
| SCHEMBL5109631 | 0.74 | GABRA1 (0.41) | ALDH1A1L3MBTL1POLB | |
| SCHEMBL4629808 | 0.74 | FFAR1 (0.36) | L3MBTL1CTSLCTSBCTSKPOLB | |
| SCHEMBL4153916 | 0.73 | CTSL (0.45) | ALDH1A1L3MBTL1CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |