Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL193315 | 0.89 | ACP3 (0.36) | ACP3MMP2MMP9MMP12GRIN2D | |
| Hydrochloric Acid SCHEMBL602954 | 0.89 | ACP3 (0.36) | ACP3MMP2MMP9MMP12GRIN2D | |
| Hydrochloric Acid SCHEMBL604657 | 0.89 | MMP2 (0.38) | ACP3MMP2MMP9MMP12 | |
| Hydrochloric Acid SCHEMBL602853 | 0.89 | RAB9A (0.36) | ACP3 | |
| SCHEMBL3788644 | 0.87 | RAB9A (0.37) | ACP3MAPK1 | |
| Hydrochloric Acid SCHEMBL601325 | 0.86 | PTPN5 (0.36) | ACP3MMP2MMP9MMP12 | |
| Hydrochloric Acid SCHEMBL193413 | 0.85 | MMP2 (0.37) | ACP3MMP2MMP9MMP12MAPK1 | |
| Hydrochloric Acid SCHEMBL193049 | 0.84 | ACP3 (0.39) | ACP3MMP2MMP9MMP12MAPK1 | |
| Hydrochloric Acid SCHEMBL604524 | 0.84 | ALDH1A1 (0.47) | ACP3MAPK1 | |
| Hydrochloric Acid SCHEMBL600629 | 0.83 | ACP3 (0.38) | ACP3MMP2MMP9MMP12MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8786932-B2 | Advanced electrode structures and electrochromic devices | NTERA, INC. (US) | 2014-07-22 | — | — | US | claimed |
| US-20120038967-A1 | ADVANCED ELECTRODE STRUCTURES AND ELECTROCHROMIC DEVICES | NTERA LIMITED (IE) | 2012-02-16 | — | — | US | claimed |
| US-8786932-B2 | Advanced electrode structures and electrochromic devices | NTERA, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-20120038967-A1 | ADVANCED ELECTRODE STRUCTURES AND ELECTROCHROMIC DEVICES | NTERA LIMITED (IE) | 2012-02-16 | — | — | US | disclosed |