Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6731864 | 0.74 | PPARG (0.59) | PPARGPPARAPPARDHTTRAB9A | |
| SCHEMBL1448948 | 0.71 | PPARG (0.49) | PPARGPPARAPPARDHTTSOAT1 | |
| Hydrochloric Acid SCHEMBL841464 | 0.70 | PPARG (0.49) | PPARGPPARAPPARDHTTSOAT1 | |
| SCHEMBL9260551 | 0.70 | PPARG (0.67) | PPARGPPARAPPARDHTTRAB9A | |
| SCHEMBL3634615 | 0.69 | FUCA1 (0.54) | HTTRAB9APOLBCHRM2CHRM1 | |
| SCHEMBL8499762 | 0.67 | TACR1 (0.51) | POLBF10 | |
| SCHEMBL9260923 | 0.67 | PPARG (0.59) | PPARGPPARAPPARDHTTRAB9A | |
| SCHEMBL20767211 | 0.67 | LMNA (0.54) | HTTGAA | |
| SCHEMBL9259746 | 0.67 | PPARG (0.66) | PPARGPPARAPPARDHTTRAB9A | |
| SCHEMBL10447010 | 0.67 | PPARG (0.56) | PPARGPPARAPPARDHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663972-A1 | THE CLAIMED INVENTION RELATES TO NOVEL 4-PIPERIDINECARBOXAMIDE AND THE USE THEREOF FOR THE PREPARATION OF MEDICAMENTS AGAINST 5-HT2A RECEPTOR-RELATED DISORDERS | Galapagos N.V. (BE) | 2006-06-07 | — | — | EP | claimed |
| WO-2005021505-A1 | THE CLAIMED INVENTION RELATES TO NOVEL 4-PIPERIDINECARBOXAMIDE AND THE USE THEREOF FOR THE PREPARATION OF MEDICAMENTS AGAINST 5-HT2A RECEPTOR-RELATED DISORDERS | GALAPAGOS NV (BE) | 2005-03-10 | — | — | WO | claimed |