Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28042691 | 0.74 | ALOX15 (0.52) | ALOX15TSHRHIF1ALMNAKDM4E | |
| SCHEMBL27898504 | 0.72 | MMP2 (0.48) | MMP2MMP7MMP14POLBFFAR1 | |
| SCHEMBL14534848 | 0.69 | MMP2 (0.60) | MMP2MMP7MMP14FFAR1 | |
| SCHEMBL270706 | 0.69 | MMP2 (0.77) | MMP2MMP7MMP14POLB | |
| SCHEMBL10803103 | 0.68 | MMP2 (0.63) | TSHRMMP2MMP7MMP14FFAR1 | |
| SCHEMBL27336528 | 0.68 | CA1 (0.53) | MMP2MMP7MMP14LMNAL3MBTL1 | |
| SCHEMBL4591973 | 0.68 | L3MBTL1 (0.50) | MMP2MMP7MMP14LMNAL3MBTL1 | |
| SCHEMBL6553661 | 0.67 | MMP2 (0.74) | MMP2MMP7MMP14POLB | |
| SCHEMBL6552246 | 0.67 | MMP2 (0.74) | MMP2MMP7MMP14POLB | |
| SCHEMBL6552547 | 0.67 | MMP2 (0.74) | MMP2MMP7MMP14POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211040-A1 | Crystal structure of chorismate synthase and uses thereof | PANTHERIX LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |
| EP-1543118-A1 | CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE AND USES THEREOF | Pantherix Ltd (GB) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004029239-A9 | CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE AND USES THEREOF | PANTHERIX LTD (GB) | 2004-06-24 | — | — | WO | disclosed |
| WO-2004029239-A1 | CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE AND USES THEREOF | PANTHERIX LTD. (GB) | 2004-04-08 | — | — | WO | disclosed |