SCHEMBL17754960

SCHEMBL17754960

COC(=O)CC(C)c1ccc(OC)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
ALDH1A1 P00352 4/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
NPC1 O15118 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PLA2G1B P04054 1/20 0.47
ATG4B Q9Y4P1 1/20 0.47
LMNA P02545 1/20 0.47
ACACB O00763 1/20 0.46
CNR2 P34972 1/20 0.46
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46
AOC3 Q16853 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8589119 0.85 L3MBTL1 (0.61) RAB9AMEN1KMT2AALDH1A1GAA
SCHEMBL2207966 0.85 FFAR1 (0.56) KMT2AALDH1A1L3MBTL1HTT
SCHEMBL2881396 0.85 ESR1 (0.48) RAB9AALDH1A1MAPTHTT
SCHEMBL13140497 0.85 ESR1 (0.48) RAB9AALDH1A1MAPTHTT
SCHEMBL14567176 0.85 ESR1 (0.48) RAB9AALDH1A1MAPTHTT
SCHEMBL17875268 0.85 ACHE (0.61) RAB9AMEN1KMT2AALDH1A1GAA
SCHEMBL14349888 0.85 ABCB11 (0.67) MAPTL3MBTL1LMNA
SCHEMBL15037436 0.84 ALDH1A1 (0.51) RAB9AMEN1KMT2AALDH1A1GAA
SCHEMBL12430380 0.84 ALOX15 (0.55) RAB9AMEN1KMT2AALDH1A1GAA
SCHEMBL16509661 0.84 ALOX15 (0.55) RAB9AMEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210040049-A1 ANTI-HCMV COMPOSITIONS AND METHODS EVRYS BIO, LLC (US) 2021-02-11 US disclosed
US-10723708-B2 Anti-HCMV compositions and methods EVRYS BIO, LLC (US) 2020-07-28 US disclosed
US-20180170884-A1 ANTI-HCMV COMPOSITIONS AND METHODS FORGE LIFE SCIENCE, LLC 2018-06-21 US disclosed
CN-107721836-A One kind synthesis 1,7 2(4 hydroxy phenyls)The method of the ketone of 1,4 diene of heptane 3 沈阳药科大学 2018-02-23 CN disclosed
WO-2016077240-A2 ANTI-HCMV COMPOSITIONS AND METHODS FORGE LIFE SCIENCE, LLC (US) 2016-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10723708-B2 Anti-HCMV compositions and methods RPL35, RPL7, RPL5 RAB9A 3682/4885MEN1 3418/4885KMT2A 3889/4885
US-20210040049-A1 ANTI-HCMV COMPOSITIONS AND METHODS RPL35, RPL7, RPL5 RAB9A 3682/4885MEN1 3418/4885KMT2A 3889/4885
US-20180170884-A1 ANTI-HCMV COMPOSITIONS AND METHODS RPL35, RPL7, RPL5 RAB9A 3682/4885MEN1 3418/4885KMT2A 3889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.