Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 4/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046492 | 0.92 | GPR4 (0.74) | GPR4 | |
| SCHEMBL6046467 | 0.90 | GPR4 (0.71) | GPR4 | |
| SCHEMBL6046464 | 0.90 | GPR4 (0.76) | GPR4 | |
| SCHEMBL6046521 | 0.89 | GPR4 (0.75) | GPR4 | |
| SCHEMBL6046490 | 0.89 | GPR4 (0.74) | GPR4 | |
| SCHEMBL6046522 | 0.88 | GPR4 (0.77) | GPR4 | |
| SCHEMBL6046475 | 0.88 | GPR4 (0.82) | GPR4 | |
| SCHEMBL6046513 | 0.87 | GPR4 (0.67) | GPR4 | |
| SCHEMBL6220831 | 0.87 | GPR4 (0.83) | GPR4 | |
| SCHEMBL6046440 | 0.87 | GPR4 (0.67) | GPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252679-A1 | Preventive and/or trerapeutic drgs for itch | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-11-09 | — | — | US | disclosed |
| US-20060239999-A1 | Preventive and/or therapeutic drugs for asthma | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-10-26 | — | — | US | disclosed |
| EP-1547616-A1 | PREVENTIVE AND/OR THERAPEUTIC DRUGS FOR ITCH | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-06-29 | — | — | EP | disclosed |
| EP-1537879-A1 | PREVENTIVE AND/OR THERAPEUTIC DRUGS FOR ASTHMA | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060239999-A1 | Preventive and/or therapeutic drugs for asthma | GPR4, HRH4, GPR3 | GPR4 1/4885 |
| US-20060252679-A1 | Preventive and/or trerapeutic drgs for itch | GPR4, TRPV1, TRPV4 | GPR4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.