Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | AURKA | O14965 | 1/20 | 0.68 |
| ▸ | DHFR | P00374 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27480006 | 0.84 | LMNA (0.48) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfaperin SCHEMBL151755 | 0.83 | LMNA (0.70) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| SCHEMBL8107423 | 0.83 | ALDH1A1 (0.60) | LMNASMN1; SMN2ALDH1A1MAPTKDM4E | |
| Sulfaperin SCHEMBL9418724 | 0.82 | LMNA (0.68) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfaperin SCHEMBL16416441 | 0.82 | LMNA (0.68) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL30080807 | 0.81 | LMNA (1.00) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL24176 | 0.81 | LMNA (1.00) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL10422849 | 0.81 | LMNA (1.00) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| SCHEMBL11267052 | 0.81 | LMNA (0.67) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| SCHEMBL26488050 | 0.81 | LMNA (0.64) | LMNAAURKADHFRTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060261267-A1 | Composite MALDI matrix material and methods of using it and kits thereof in MALDI | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2006-11-23 | — | — | US | claimed |
| US-20060261267-A1 | Composite MALDI matrix material and methods of using it and kits thereof in MALDI | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2006-11-23 | — | — | US | disclosed |