Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047581 | 0.85 | ACHE (0.50) | ALOX5HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6047623 | 0.85 | ALDH1A1 (0.47) | ALOX5RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL5887069 | 0.83 | CA12 (0.38) | ALOX5RAB9ASMN1; SMN2NPC1TP53 | |
| SCHEMBL6047658 | 0.81 | NPC1 (0.41) | RAB9ASMN1; SMN2NPC1KMT2AL3MBTL1 | |
| SCHEMBL5886818 | 0.78 | CA12 (0.39) | RAB9ASMN1; SMN2NPC1TP53KMT2A | |
| SCHEMBL5887219 | 0.76 | MAPT (0.42) | ALOX5HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5887097 | 0.75 | ALOX5 (0.40) | ALOX5HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5887556 | 0.75 | ALOX5 (0.40) | ALOX5HPGDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL5887724 | 0.75 | GSK3B (0.41) | HPGDSMN1; SMN2GSK3BKMT2AMEN1 | |
| SCHEMBL4808801 | 0.74 | APP (0.38) | HPGDRAB9ASMN1; SMN2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006501194-A | — | — | 2006-01-12 | — | — | JP | claimed |
| EP-1525190-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004007463-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-01-22 | — | — | WO | claimed |