Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.38 |
| ▸ | CTSS | P25774 | 8/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5606158 | 0.77 | CTSK (0.38) | CTSKCTSSCTSLCTSBEPHX1 | |
| SCHEMBL5606156 | 0.77 | CTSK (0.38) | CTSKCTSSCTSLCTSBEPHX1 | |
| SCHEMBL6048161 | 0.76 | CTSS (0.46) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5581496 | 0.74 | HTT (0.42) | CTSKCTSSCTSLCTSBCTSD | |
| SCHEMBL6660147 | 0.73 | CTSS (0.47) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL5696946 | 0.71 | DPP4 (0.35) | CTSKCTSSCTSLCTSBCTSD | |
| SCHEMBL6660154 | 0.70 | EPHX1 (0.40) | CTSKCTSSCTSLCTSBCTSD | |
| SCHEMBL6657069 | 0.69 | CTSS (0.48) | CTSKCTSSCTSLCTSB | |
| SCHEMBL28272670 | 0.68 | SERPINE1 (0.43) | CTSKCTSSMEN1GAAKMT2A | |
| SCHEMBL14167278 | 0.67 | CTSK (0.45) | CTSKCTSSCTSLCTSBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716158-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering Aktiengesellschaft (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005074904-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |