Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.46 |
| ▸ | CTSK | P43235 | 15/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660147 | 0.85 | CTSS (0.47) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6657069 | 0.81 | CTSS (0.48) | CTSSCTSKCTSLCTSB | |
| SCHEMBL6048166 | 0.76 | CTSK (0.38) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5696941 | 0.74 | PPARG (0.43) | CTSSCTSKCTSLCTSB | |
| SCHEMBL2367381 | 0.72 | CTSK (0.48) | CTSSCTSKCTSLCTSB | |
| SCHEMBL903742 | 0.72 | CTSK (0.48) | CTSSCTSKCTSLCTSB | |
| SCHEMBL2367189 | 0.72 | CTSK (0.48) | CTSSCTSKCTSLCTSB | |
| SCHEMBL3820796 | 0.70 | CTSK (0.39) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5517840 | 0.70 | CTSL (0.72) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5517842 | 0.70 | CTSL (0.72) | CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716158-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | Schering Aktiengesellschaft (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005074904-A2 | SILINANE COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |