Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30547691 | 1.00 | KMT2A (0.48) | KMT2AMEN1LMNAMAPTESR1 | |
| SCHEMBL9838267 | 0.83 | KMT2A (0.49) | KMT2AMEN1LMNAMAPTESR1 | |
| SCHEMBL27594448 | 0.75 | KMT2A (0.39) | KMT2AMEN1LMNAMAPTESR1 | |
| SCHEMBL15132784 | 0.72 | KMT2A (0.48) | KMT2AMEN1LMNAMAPTESR1 | |
| SCHEMBL9099722 | 0.72 | KMT2A (0.48) | KMT2AMEN1LMNAMAPTESR1 | |
| SCHEMBL6632471 | 0.71 | ABL1 (0.46) | LMNAMAPTALDH1A1MAPK1CYP1A2 | |
| SCHEMBL6567692 | 0.70 | ALDH1A1 (0.56) | KMT2AMEN1LMNAMAPTESR1 | |
| SCHEMBL14143399 | 0.70 | ALDH1A1 (0.56) | KMT2AMEN1LMNAMAPTESR1 | |
| SCHEMBL9099532 | 0.68 | KMT2A (0.43) | KMT2AMEN1LMNAMAPTESR1 | |
| SCHEMBL4044632 | 0.68 | KMT2A (0.44) | KMT2AMEN1LMNAMAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060282123-A1 | Electrical devices and anti-scarring agents | ANGIOTECH INTERNATIONAL AG (CH) | 2006-12-14 | — | — | US | disclosed |