Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRAT | P43155 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 6/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL3095441 | 0.97 | TSHR (0.50) | TSHRALDH1A1LMNAAPEX1SLC22A16 | |
| Glycinebetaine SCHEMBL7753166 | 0.93 | TSHR (0.46) | TSHRALDH1A1LMNAAPEX1SLC22A16 | |
| Glycinebetaine SCHEMBL9281697 | 0.92 | TSHR (0.55) | TSHRALDH1A1LMNAAPEX1SLC22A16 | |
| Betaine SCHEMBL31467313 | 0.91 | — | — | |
| Glycinebetaine SCHEMBL8678519 | 0.91 | TSHR (0.53) | TSHRALDH1A1LMNAAPEX1SLC22A16 | |
| Glycinebetaine SCHEMBL4900209 | 0.91 | — | — | |
| Glycinebetaine SCHEMBL2803780 | 0.91 | TSHR (0.53) | TSHRALDH1A1LMNAAPEX1SLC22A16 | |
| Glycinebetaine SCHEMBL7739 | 0.91 | — | — | |
| Glycinebetaine SCHEMBL11008279 | 0.89 | TSHR (0.46) | TSHRALDH1A1LMNAAPEX1SLC22A16 | |
| Glycinebetaine SCHEMBL8725957 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234478-A | Oral composition | 花王株式会社 | 2024-06-21 | — | — | CN | claimed |
| CN-115701975-B | Cleaning agent composition for oral cavity installation device | 花王株式会社 | 2024-02-09 | — | — | CN | claimed |
| US-20230203402-A1 | CLEANING COMPOSITION FOR ORAL APPLIANCE | KAO CORPORATION (JP) | 2023-06-29 | — | — | US | claimed |
| WO-2023084922-A1 | COMPOSITION FOR ORAL CAVITY | 花王株式会社 | 2023-05-19 | — | — | WO | claimed |
| EP-4166639-A1 | CLEANING AGENT COMPOSITION FOR INTRAORALLY MOUNTED APPLIANCES | Kao Corporation (JP) | 2023-04-19 | — | — | EP | claimed |
| CN-115701975-A | Cleanser composition for oral cavity-mounted appliance | 花王株式会社 | 2023-02-14 | — | — | CN | claimed |
| CN-115029928-A | Water-repellent and oil-repellent agent composition and preparation method and application thereof | 福可新材料(上海)有限公司 | 2022-09-09 | — | — | CN | claimed |
| CN-107106445-B | Liquid oral composition in foam-discharging container | 花王株式会社 | 2020-08-21 | — | — | CN | claimed |
| CN-104159563-B | skin cleanser composition | 花王株式会社 | 2016-08-24 | — | — | CN | claimed |
| CN-102947436-B | Concentrated liquid detergent composition and process for producing the same | SHISEIDO CO LTD | 2015-01-07 | — | — | CN | claimed |
| US-7147843-B2 | Hydrophobic polyether urethane C23+ endcapped (especially from 2-decyltetradecanol) and cationic surfactant; also cleaning agent containing the modified polymer and anionic surfactant and/or ampholytic surfactant. | SHISEIDO COMPANY, LTD. (JP) | 2006-12-12 | — | — | US | claimed |
| US-7138365-B2 | Thickener comprising hydroxyalkylated polyhydric alcohol ether compound and high-viscosity liquid detergent composition containing the same | KAWAKEN FINE CHEMICAL CO., LTD. (JP) | 2006-11-21 | — | — | US | claimed |
| CN-1242037-C | Detergent composition | NOF CORP (JP) | 2006-02-15 | — | — | CN | claimed |
| US-20040214739-A1 | Thickener comprising hydroxyalkylated polyhydric alcohol ether compound and high-viscosity liquid detergent composition containing the same | KAWAKEN FINE CHEMICALS, CO., LTD. (JP) | 2004-10-28 | — | — | US | claimed |
| CN-1537158-A | Detergent composition | 日本油脂株式会社 | 2004-10-13 | — | — | CN | claimed |
| EP-1411112-A1 | THICKENER COMPRISING HYDROXYALKYLATED POLYHYDRIC ALCOHOL ETHER COMPOUND AND HIGH−VISCOSITY LIQUID DETERGENT COMPOSITION CONTAINING THE SAME | Kawaken Fine Chemicals Co., Ltd. (JP) | 2004-04-21 | — | — | EP | claimed |
| EP-1295591-A1 | HAIR GROOMING PREPARATION | SHISEIDO COMPANY LIMITED (JP) | 2003-03-26 | — | — | EP | claimed |
| US-20030012761-A1 | Hair grooming preparation | SHISEIDO COMPANY, LTD. (JP) | 2003-01-16 | — | — | US | claimed |
| CN-1383377-A | Hair grooming compsns. | SHISEIDO CO LTD (JP) | 2002-12-04 | — | — | CN | claimed |
| US-6417146-B1 | LIQUID DETERGENTS OF SURFACTANT BLEND | KAO CORPORATION (JP) | 2002-07-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030012761-A1 | Hair grooming preparation | SHH, ITCH, SPAST | TSHR 2939/4885ALDH1A1 3604/4885LMNA 3519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.