Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900560 | 0.86 | ALDH1A1 (0.47) | ENPP2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3900556 | 0.84 | NPC1 (0.38) | ENPP2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3911208 | 0.83 | ITGB3 (0.42) | ENPP2NPC1RAB9AMEN1LMNA | |
| SCHEMBL3900029 | 0.78 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL3911221 | 0.77 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL3933899 | 0.72 | SMN1; SMN2 (0.65) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL13938567 | 0.71 | NOS2 (0.55) | ENPP2MAPTGAAMEN1LMNA | |
| SCHEMBL27815401 | 0.69 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL998689 | 0.68 | RAB9A (0.46) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL3449454 | 0.67 | MEN1 (0.46) | NPC1SMN1; SMN2MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1669352-A1 | THIAZOLINE DERIVATIVE AND USE OF THE SAME | Takeda Pharmaceutical Company Limited (JP) | 2006-06-14 | — | — | EP | disclosed |