SCHEMBL6049287

SCHEMBL6049287

CCC(CC)=NCc1cccc(CN=C(CC)CC)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 5/20 0.55
GRIN2D O15399 2/20 0.55
GRIN3B O60391 2/20 0.55
GRIN1 Q05586 2/20 0.55
GRIN2A Q12879 2/20 0.55
GRIN2C Q14957 2/20 0.55
GRIN3A Q8TCU5 2/20 0.55
NOS2 P35228 4/20 0.52
NOS1 P29475 3/20 0.52
NOS3 P29474 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP3A4 P08684 1/20 0.52
NFKB1 P19838 1/20 0.52
HTR1A P08908 1/20 0.48
ADRA2A P08913 1/20 0.48
MAOA P21397 1/20 0.48
DRD1 P21728 1/20 0.48
SLC6A2 P23975 1/20 0.48
ADRA1A P35348 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29037227 0.91 NOS1 (0.67) GRIN2BGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11306773 0.81 TSHR (0.48) GRIN2BGRIN1SMN1; SMN2ALDH1A1
SCHEMBL5709545 0.68 NOS2 (0.50) GRIN2BGRIN2DGRIN3BGRIN1GRIN2A
1400W SCHEMBL524310 0.68 NOS2 (1.00) GRIN2BGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL11097294 0.68 GRIN2B (0.54) GRIN2BGRIN2DGRIN3BGRIN1GRIN2A
1400W SCHEMBL29386443 0.67 NOS2 (1.00) GRIN2BGRIN2DGRIN3BGRIN1GRIN2A
1400W SCHEMBL3115597 0.67 NOS2 (1.00) GRIN2BGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL975222 0.67 TAAR1 (0.43) GRIN2BGRIN2DGRIN3BGRIN1GRIN2A
Hydrogen Peroxide SCHEMBL11520377 0.66 TP53 (0.63) GRIN2BGRIN2DGRIN3BGRIN1GRIN2A
Methyl Alcohol SCHEMBL28745884 0.66 TP53 (0.55) GRIN2BGRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11613656-B2 Method for preventing hardener compounds to be formed from hardener precursors in an aerosol formulation and a two-component aerosol formulation WISESPRAY INTERNATIONAL LTD (FI) 2023-03-28 US claimed
EP-3635062-B1 A METHOD FOR PREVENTING HARDENER COMPOUNDS TO BE FORMED FROM HARDENER PRECURSORS AND EXTENDING SHELF LIFE OF THE DISPERSION WISESPRAY INT OY (FI) 2022-03-02 EP claimed
US-20220002561-A1 A METHOD FOR REDUCING WATER CONTENT OF AN EPOXY OR/AND POLYURETHANE PAINT DISPERSION AND AN EPOXY OR/AND POLYURETHANE PAINT DISPERSION WISESPRAY INTERNATIONAL OY (FI) 2022-01-06 US claimed
EP-3387074-B1 A METHOD FOR PREVENTING HARDENER COMPOUNDS TO BE FORMED FROM HARDENER PRECURSORS IN AN AEROSOL FORMULATION AND A TWO-COMPONENT AEROSOL FORMULATION PAINT & AEROSOL CONSULTANCY (NL) 2020-09-30 EP claimed
US-20200190338-A1 Method for Preventing Hardener Compounds to be Formed from Hardener Precursors and Extending Shelf Life of the Dispersion MASTON OY (FI) 2020-06-18 US claimed
US-20180362776-A1 A method for preventing hardener compounds to be formed from hardener precursors in an aerosol formulation and a two-component aerosol formulation PAINT & AEROSOL CONSULTANCY (NL) 2018-12-20 US claimed
EP-3412735-A1 THE PAINT FORMING PRESSURIZED DISPERSION HAVING AN EXTENDED SHELF LIFE AND THE METHOD FOR PREPARING THEREOF Maston OY (FI) 2018-12-12 EP claimed
US-11613656-B2 Method for preventing hardener compounds to be formed from hardener precursors in an aerosol formulation and a two-component aerosol formulation WISESPRAY INTERNATIONAL LTD (FI) 2023-03-28 US disclosed
CN-110997827-B Method for preventing formation of hardener compound from hardener precursor and extending shelf life of dispersion 马斯顿公司 2022-10-28 CN disclosed
EP-3635062-B1 A METHOD FOR PREVENTING HARDENER COMPOUNDS TO BE FORMED FROM HARDENER PRECURSORS AND EXTENDING SHELF LIFE OF THE DISPERSION WISESPRAY INT OY (FI) 2022-03-02 EP disclosed
US-20220002561-A1 A METHOD FOR REDUCING WATER CONTENT OF AN EPOXY OR/AND POLYURETHANE PAINT DISPERSION AND AN EPOXY OR/AND POLYURETHANE PAINT DISPERSION WISESPRAY INTERNATIONAL OY (FI) 2022-01-06 US disclosed
US-11028274-B2 Method for preventing hardener compounds to be formed from hardener precursors and extending shelf life of the dispersion WISESPRAY INTERNATIONAL LTD (FI) 2021-06-08 US disclosed
EP-3387074-B1 A METHOD FOR PREVENTING HARDENER COMPOUNDS TO BE FORMED FROM HARDENER PRECURSORS IN AN AEROSOL FORMULATION AND A TWO-COMPONENT AEROSOL FORMULATION PAINT & AEROSOL CONSULTANCY (NL) 2020-09-30 EP disclosed
US-20200190338-A1 Method for Preventing Hardener Compounds to be Formed from Hardener Precursors and Extending Shelf Life of the Dispersion MASTON OY (FI) 2020-06-18 US disclosed
US-20180362776-A1 A method for preventing hardener compounds to be formed from hardener precursors in an aerosol formulation and a two-component aerosol formulation PAINT & AEROSOL CONSULTANCY (NL) 2018-12-20 US disclosed
EP-3412735-A1 THE PAINT FORMING PRESSURIZED DISPERSION HAVING AN EXTENDED SHELF LIFE AND THE METHOD FOR PREPARING THEREOF Maston OY (FI) 2018-12-12 EP disclosed
EP-1362876-B1 ONE-PACK MOISTURE-CURABLE EPOXY RESIN COMPOSITION KONISHI CO LTD (JP) 2006-03-08 EP disclosed
US-20040019140-A1 One-pack moisture-curable epoxy resin composition KONISHI CO., LTD. (JP) 2004-01-29 US disclosed
EP-1362876-A1 ONE-PACK MOISTURE-CURABLE EPOXY RESIN COMPOSITION KONISHI CO., LTD. (JP) 2003-11-19 EP disclosed